Tuesday, 20 September 2022
Schedule : Back to Miss Carrie Barrett

Depression and Quality of Life Amongst People Affected by Filarial Lymphoedema: Determining the Sociodemographic and Physical Risk Factors, and the Impact of Enhanced Self-Care Intervention.

Tue20  Sep11:55am(15 mins)
Virtual meeting


C Barrett1; J Chiphwanya2; D Matipula2; L Chaponda2; J Turner1; J Read3; M Taylor1; L Kelly-Hope4
1 Liverpool School of Tropical Medicine, UK;  2 Ministry of Health, Malawi, UK;  3 Lancaster University, UK;  4 University of Liverpool, UK


Background: Lymphatic filariasis (LF) is a major cause of disfiguring and disabling lymphoedema. This study aims to: i) determine the prevalence of and risk factors associated with depression and low quality of life (QOL) in lymphoedema patients; ii) understand if implementation of enhanced self-care (ESC) impacts depression and QOL. Methodology: A prospective cohort of ~300 patients from two regions of Malawi (North/South) was conducted over six months. Lymphoedema patients were surveyed at baseline then trained in ESC; hygiene, deep-breathing, massage and leg exercises. Follow-up surveys at 3- and 6-months assessed depression and QOL using a Likert scale Patient Health Questionnaire (PHQ-9) and a adapted LF Specific QOL Questionnaire (LFSQQ). Data were stratified by the three survey time periods. Associated sociodemographic and clinical conditions (lymphoedema severity, acute dermatolymphangioadenitis (ADLAs; secondary bacteria infections) risk factors were identified using univariable beta regression. Results: Baseline data on 309 patients found that 23% (95%CI, 18%-28%) reported mild/moderate depression and 31% (95%CI, 26%-37%) reported moderately/severely low QOL. A higher number of ADLAs in last 6 months was significantly associated with higher depression and lower QOL scores (pConclusion: Filarial lymphoedema is associated with a high prevalence of depression and lower QOL. ESC is a promising home-based intervention that national LF elimination programmes could readily scale up and help to reduce depression and improve quality of life amongst those affected.

Hosted By

British Society for Parasitology (BSP)

We are science based Charitable Incorporated Organisation