ELRIG's Therapeutic OLIGOs and European Chemical Biology Symposium 2023

Posters

Ellen Fay
Trinity College Dublin
Ireland
1From Fragments to Oligonucleotides: Two-Step Validation of Metal-Binding Groups for Targeting the DNA Damage Repair Enzyme SNM1A
Tanja Miletic
EU-OPENSCREEN ERIC
Germany
2Accelerating small molecule drug discovery by a powerful collaborative approach
Robert Ives
Durham University
3Exploring Novel Three-Dimensional Shape Diversity in Shapeshifting Molecules
Heather Gildie
Helleday Laboratory
Sweden
4Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function.
Anna Rydzik
AstraZeneca
Sweden
5Uptake of chemically modified antagomirs by lung relevant cell systems.
Kai Liu
AstraZeneca
Sweden
6Multiomics analysis of naturally efficacious lipid nanoparticle coronas reveals high-density lipoprotein is necessary for function
Victoria Mora
EU-OPENSCREEN ERIC
Germany
7Identify new biological activities of your compounds
Paula Novo Valencia
Universidade da Coruña
Spain
9DNA Binding of a Cucurbit[8]uril-Mediated 4,4′-Bipyridinium−Peptide Dimer
Kamil Kamiński
FutureSynthesis
Poland
10Innovative biogels delivering miRNAs into skin models.
SAFA BAZAZ
Karolinska Institutet
Sweden
11Using heparin analogues to improve the transduction efficiency of gene therapy viral vectors
Juanitta Vibeke Julsgart
Fida Biosystems ApS
Denmark
13Flow induced dispersion analysis (FIDA) to measure gRNA-nuclease interactions for CRISPR-Cas development.
Ronan Kelly
University College Dublin
Ireland
14Scalable One-Pot Liquid Phase Oligonucleotide Synthesis Enhanced By Organic Solvent Nanofiltration
Aizhan Rakhmetullina
Institute of Biochemistry and Biophysics
Poland
15Binding Site piRNA Clusters as Possible Regulators of Protein-Coding Gene Expression
Matthew Lindon
LIDDS AB
Sweden
16NZ-TLR9 shows antitumoral activity against both treated and untreated tumors in various rodent models and is characterised by a promising safety and PK/PD profile.
Irene Whitney
Honeycomb Biotechnologies
United States
17Preventing Sample Bias in scRNAseq introduced by Cryopreservation: A Solid Tumor Case Study
Marina Mínguez-Toral
Centro de Investigaciones Biológicas Margarita Salas (CIB-CSIC)
Spain
18Computational approaches to modulate innate immunity: Toll-like receptors 2 and 4
Adam Dickey
SciLifeLab
Sweden
19Optimisation of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo Guanine DNA Glycosylase 1
Martin Popr
CZ-OPENSCREEN (IMG Prague)
Czech Republic
20AUTOMATED COMPOUND MANAGEMENT PIPELINE AT THE CZ-OPENSCREEN
Krzysztof Waligórski
FUTUREsynthesis sp. z o.o.
Poland
21Hybrid support for scalable, high-performance oligonucleotide synthesis
Antonia Konczwald
Beckman Coulter Life Sciences
Germany
22Released N-linked glycan analysis employing automated sample preparation on a Biomek i5 liquid handler
Antonia Konczwald
Beckman Coulter Life Sciences
Germany
23High-throughput process development and screening of chromatographic conditions on a Biomek i7 Dual Hybrid automated workstation with CytivaPreDictor™plates
Antonia Konczwald
Beckman Coulter Life Sciences
Germany
24Miniaturized DRUG-seq on the Echo 655T acoustic liquid handler and BRB-seq on the Biomeki7 Dual Hybrid Workstation
Massimiliano Gaetani
Karolinska Institute
Sweden
25PISA-based assays for High Throughput and High Confidence Target Deconvolution and MoA Elucidation through Deep MS-based Proteomics
Bernhard Schmierer
SciLifeLab and Karolinska Institutet
Sweden
26Unlock the power of CRISPR at the SciLifeLab CRISPR Functional Genomics Unit
Weixiao Yuan Wahlgren
Chemical Biology Consortium Sweden Gothenburg Node
Sweden
27Chemical Biology Consortium Sweden - a SciLifeLab national research infrastructure
Sofie Albinsson Högberg
AstraZeneca
Sweden
28Implementation of one-step RT-qPCR to accelerate oligo discovery
Ctibor Škuta
CZ-OPENSCREEN, Institute of Molecular Genetics of the Czech Academy of Sciences
Czech Republic
29European Chemical Biology Database
Soňa Gurská
IMTM, Palacky Univesity
Czech Republic
32Determination of novel inhibitors of carbonic anhydrase IX by HTS compaign.
Anna-Lena Gustavsson
Karolinska Institutet SciLifeLab
Sweden
33The SciLifeLab Chemical Biology & Genome Engineering Platform - Turning phenotypic observations into mechanistic insights
Alva Abrahamsson
Umeå University
Sweden
34The G-quadruplex ligand’s guide to selectivity - Development of a G4 Ligand-Oligonucleotide Modality that Selectively Targets Individual G4 DNA Structures
Urszula Cojg
Silesian University of Technology
Poland
35Effects of hormones on calcium homeostasis in HCT116 cells
Patrycja Mandera
Silesian University of Technology
Poland
36In search of factors inducing changes in aquaporin expression levels in civilization diseases
Antonio Carlesso
University of Göteborg
Sweden
37Deconvoluting the binding of therapeutic oligonucleotides through a multi scale in silico approach
Lara Sweetapple
Karolinska Institute
Sweden
38Understanding microRNA function through biophysical investigation
Melania Minoia
Drug Discovery and Development platform
Sweden
39Biochemical and Cellular Assay unit (BCA) - at the National Drug Discovery and Development platform (DDD) at SciLifeLab, Sweden.
Martin Svensson
AstraZeneca, Discovery Sciences, Compound Synthesis & Management
Sweden
40“Next Generation Therapeutics and Aqueous Workflows: Challenges and Opportunities for Compound Management”
Birgit Meindl
TU Wien
Austria
41Modified Peptide Nucleic Acids for RNA-Targeting
Matthijs Pijnappel
Recipharm
Sweden
42Method development for quantification of oligonucleotides by LC-MS in biological samples suitable for pre-clinical studies
Daniel van Leeuwen
AstraZeneca
Sweden
43Deciphering molecular details of ASO:protein interactions which drive toxicity
Anna Spanopoulou
Eurofins Genomics Europe Pharma and Diagnostic Products & Services Synthesis GmbH
Germany
44High performance, high throughput oligonucleotide synthesis for diagnostic and therapeutic applications
Antonio Pombinho
i3S
Portugal
45PT-OPENSCREEN: The Portuguese Infrastructure for Chemical Biology and Genetics
Sofie Devacht
Merck
Germany
47Next-Gen Sequencing Oligos (NGSO) for Consistent and Efficient Use in the Therapeutic Oligos Workflow
Bruna Marchi
University of Gothenburg
Sweden
48The role of Uncaria tomentosa extract and its compounds as antioxidants in the expression of proteins involved in insulin signaling pathway
Bo Lundgren
SciLifeLab, Stockholm university
Sweden
50Drug Discovery and Development platform - The national infrastructure that transforms your academic research into novel therapies at SciLifeLab, Sweden
Gabriela Vazquez Rodriguez
BioReperia AB
Sweden
51The zebrafish tumor xenograft model (ZTX) as a tool to accelerate drug discovery and development
Yasmin Andersson
Pelago Bioscience AB
Sweden
54Profiling Targeted Protein Degradation using the Cellular Thermal Shift Assay (CETSA®).
Johannes Wikström
Ribocure Pharmaceuticals AB
Sweden
55Targeting liver angiotensinogen using a GalNAc-siRNA improves cardiac remodeling in spontaneously hypertensive rats
Natalia Dovlatova
Platelet Services Ltd.
56Assessment in vitro of potential effects of oligonucleotides on platelet function
Alzbeta Srovnalova
Palacky University
Czech Republic
58Characterization of anti-cancer effects for novel benzodiazepine derivatives
Count: 49