6A novel ensemble approach to providing small molecule support for validation of cellular targets confirms that glycolysis is a viable antiproliferative strategy in leukemic cells.
12Predicting adverse immune reactions to biopharmaceuticals using a human in-vitro skin explant test: a promising tool for biopharmaceutical R&D development
29A New Poster AUse of AssayQuant Fluorogenic Peptides to Determine the Mechanism of Compound Inhibition and Potency for a Range of Tyrosine and Serine/Threonine Kinases. bstract
31Pyrido[3,4-d]pyrimidin-4(3H)-one C8-derivatisation: The identification of potent and cell penetrant dual KDM4/KDM5 histone lysine demethylase inhibitors
41Detection of Phospho-Akt (Ser 473) as an Indication of PI3K Pathway Activation in MCF7 Cells Using the Labcyte Echo® Liquid Handler and Cisbio’s HTRF® Cellular Assay Kit
90Characterization of hTERT-immortalized Prostate-derived Stromal and Epithelial Cells: an Authentic in vitro Model for Tumour Microenvironment Studies
109Investigating the Effects of New Lysyl Oxidase (LOX) and Lysyl Oxidase Like 2 (Loxl2) Inhibitors on Clear Cell Renal Cell Carcinoma Cells (ccRCC) in Vitro
125A novel inhibitor of PAICS, an enzyme in the de novo purine synthetic pathway, exhibits selectivity and elicits cell cycle arrest resulting in a reduction in tumour growth
133High-Throughput Fluorescence Measurements of Action Potential and Ca2+ Transients in Human iPSC-Derived Cells for Toxicity Screening and Drug Discovery
