Research & Innovation 2015 - Accelerating Early Discovery

Posters

Herring
Dominic Herring
BioTek Instruments UK
United States
5Combining Kinetic Ligand Binding and 3D Tumor Invasion Technologies to Assess Drug Residence Time and anti-Metastatic Effects of CXCR4 Inhibitors
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Herring
Dominic Herring
BioTek Instruments UK
United States
6Cellular Analysis of 3D Spheroid-Based Tumor Invasion Assays
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Herring
Dominic Herring
BioTek Instruments UK
United States
7Phenotypic and Epigenetic Mechanism of Action Determinations of Histone Methylase and Demethylase Inhibitors using Digital Widefield Microscopy
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March
Nikki March
CRUK Manchester Institute
8Inhibition of SMARCA2: a novel target for SMARCA4-deficient lung adenocarcinoma
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Robertson
Alasdair Robertson
SAL Scientific Ltd
9Optimised Conditions for Cell Growth in Defined Media
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Ivanov
Delyan Ivanov
University of Nottingham
10Co-culture spheroids for phenotypic preclinical assessment of direct drug delivery to paediatric brain tumours
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Alam
Masih Alam
ImmunoSYS Ltd
11A Novel Ultra-sensitive Assay for Bio-analysis of Innovative Medicines
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GEORGE
VINOJ GEORGE
University of Nottingham
12High Efficiency Differentiation and Maturation of Human Pluripotent Stem Cell (hPSC)-derived Cardiomyocytes
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Dangelo
Jean Marc Dangelo
Hamamatsu Photonics France S.A.R.L.
13Electric Field Stimulation (EFS) of cardiomyocytes using Hamamatsu FDSS/μCELL
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Dangelo
Jean Marc Dangelo
Hamamatsu Photonics France S.A.R.L.
14Measurements of Ca2+ response in human iPSC-derived peripheral neurons by electric field stimulation in FDSS/μCELL
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Dangelo
Jean Marc Dangelo
Hamamatsu Photonics France S.A.R.L.
15Safety toxicity with cardiomyocytes derived from induced human pluripotent stem cells on FDSS platform
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Davenport
Steve Davenport
IntelliCyt Corporation
United States
16Miniaturization of High Throughput Flow Assays for 384-Well Low Volume and 1536-Well Plates: Detection of Highly Multiplexed Analytes in 6 µL Assays with the iQue Screener and MultiCyt QBeads
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Murray
David Murray
AstraZeneca plc
17Screening for Cell Death - a comparison of methods
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Riss
Terry Riss
Promega Corporation
United States
18Measuring Live Cells and Dead Cells in Real Time for Days Using a Plate Reader
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Walter
Joanne Walter
EuroScitech
19LabMinds Revo – an automated solution preparation system that releases scientific minds from the burden of procedural lab tasks.
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Burke
Anne Burke
EuroScitech
20Difficult to Express Proteins made easy with the Drosophila S2 based ExpreS2 system
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Cribbes
Scott Cribbes
Nexcelom BioScience Ltd
21Cell-Mediated Cytotoxicity Assay by High-Throughput Direct Cell Counting in Microplates using Fluorescence-Based Image Cytometry
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Moens
Nathalie Moens
King's College London
22Development of a high-content platform to characterise large numbers of induced pluripotent stem cell lines
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Bridgland-Taylor
Matt Bridgland-Taylor
AstraZeneca
23Combination of an iPS cardiomyocyte Calcium flux screen and functional ion channel data to influence compound selection early in drug discovery.
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Payne
Sarah Payne
TTP Labtech Ltd
24Rapid analysis of 3D tumour cultures in soft agar and on ultra-low attachment plates using a laser scanning imaging system
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Payne
Sarah Payne
TTP Labtech Ltd
25An Integrated Solution to Provide Phenotypic Primary and Secondary Screening of a Full Deck Compound Library
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Payne
Sarah Payne
TTP Labtech Ltd
26A new approach to run target- and phenotypic -based antibody screening to identify better therapeutic antibodies
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Legris
Valerie Legris
The Electrospinning Company
27Liver cancer cells grown in 3D in the Mimetix scaffold regain a primary-like phenotype
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Svensson Dalén
Jennie Svensson Dalén
Cellectricon
Sweden
28Efficient transfection of native sensory neurons
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Feeney
Kate Feeney
DiscoveRx
29Rational design of dual kinase-bromodomain inhibitors for therapeutic polypharmacology
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Baxter
Andrew Baxter
DiscoveRx
30Elucidating Mechanisms of Toxicity Using Phenotypic Data from Human Primary Cell Systems –a Chemical Biology Approach for Thrombosis-Related Side Effects
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Thomas
Dave Thomas
Sartorius Stedim Biotech
31Automated scale up and cryopreservation of stem cells for drug discovery research programmes
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Lamb
Stephen Lamb
Asymptote Ltd
33Enabling high throughput screening with cryopreserved multiwell plates
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Count: 28