Authors
S Wyllie1; 1 University of Dundee, UKDiscussion
Dr Susan Wyllie has more than 15 years of experience studying kinetoplastid biology. Specifically, her research has focused on determining the mechanisms of action and mechanisms of resistance of drugs targeting kinetoplastid parasites. Her talk will detail her recent work leading the Mode of Action Group at the University of Dundee. Specifically, she will detail the groups: -Use of complementary methodologies in the fields of genomics, chemical proteomics and cell biology to determine the modes of action and specific molecular targets of phenotypically-active compounds -Development of new genetic and cell biology tools to facilitate the study of drug mechanism of action in the kinetoplastids -Functional characterisation of novel targets -Development of novel cell-based assays to exploit high value drug targets