The recent resolution revolution in cryo-EM has fundamentally changed its utility as a tool in modern structural biology, and therefore opened up new possibilities in drug discovery. I will describe the basic methodologies, and explain how improved resolution has been achieved. I will also illustrate what is currently achievable, using examples from projects in structural virology and anti-microbial resistance, and highlight the potential for further improvements.
The European Laboratory Research & Innovation Group
Our Vision : To provide outstanding, leading edge knowledge to the life sciences community on an open access basis
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