Translating Ideas into Therapies 2021- Co-hosted with the British Pharmacological Society

Posters

Newman Osafo
Kwame Nkrumah University of Science and Technology
Ghana
1Ref: PP018 Anti-ulcerative colitis potential of the hydroethanolic extract of the dried fruits of Xylopia aethiopica in rats
Yolanda Calle
University of Roehampton
2Therapeutic drugs promote differentiation of Acute Myeloid Leukaemia (AML) blasts into a migratory and chemo-resistant phenotype facilitated by the bone marrow microenvironment.
Khaled ALROSAN
Keele university
3P006 Using nanoparticles to improve the therapeutic index of navitoclax for the treatment of ovarian cancer
Matthew Swift
University of Nottingham
4Ref: P008 Inhibition of SPRK1 in vivo in mice reduces nociceptive behaviour in a model of chemotherapeutic peripheral neuropathy.
Álvaro Hernández
ZeClinics
Spain
5A zebrafish-based pipeline for in vivo quality control of new Cas9 variants
Elly Rankin
Miltenyi Biotec
6Isolation of functional cells straight from buffy coat, LRSC, and Leukopak®
Miriam Pasquini
Exscientia
7Ref: P013 Unravelling the druggability of DNA helicases through enzyme kinetics and mathematical modelling
David Davies
Antabio
France
8Ref: P009 SAR Leading to the Discovery of ANT3310, a Novel DBO β-lactamase Inhibitor which Potentiates Meropenem Activity Against Carbapenemase-Resistant Acinetobacter baumannii (CRAB) and Enterobacteriaceae (CRE)
CHITARANJAN MAHAPATRA
University of California San Francisco
United States
9Ref: P021 Computational Study of SARS-CoV-2 Infection Inhibitor Hydroxychloroquine on Cardiac Toxicity
Stéphanie Andrade
Faculty of Engineering of University of Porto
Portugal
10Ref: P007 Interaction of Aβ peptide with vitamin B12: Implication for the therapy of Alzheimer’s disease
Sara Alhaidar
King Saud University
Saudi Arabia
11Ref: P011 Role of G Protein-Coupled Receptor kinase 5 in Animal Model of Cardiac Hypertrophy
Samaher Qaboli
King Saud University
Saudi Arabia
12Ref: P012 Sitagliptin Mitigates Diabetic Nephropathy in a Rat Model of Streptozotocin-Induced Type 2 Diabetes: Possible Role of PTP1B/JAK-STAT Pathway
Jon Waterman-Smith
Nilogen Oncosystems
United States
13Evaluating the effectiveness of ADC targeted therapy in a patient-derived ex vivo tumoroid model, 3D-EXplore, for quantitative tumor cell killing
Nikita Patel
QMUL
14Ref: P015 Inhibition of Bruton’s tyrosine kinase reduces organ injury and dysfunction in a rat model of severe haemorrhage
SAMSON KOSEMANI
The University of Ibadan
Nigeria
15Ref: P022 Fraction from Calliandra portoricensis Reduces 7,12- Dimethylbenz(a)Anthracene-Induced Mammary Tumors in Wistar Rats
Abdullah Al Matrafi
IAU
Saudi Arabia
16Ref: P016 Identifying and repurposing drugs capable of stabilizing multiple variants of the SARS-Cov-2 S-glycoprotein in a closed conformation, using in silico techniques
Shireen Mohammad
Barts and the London School of Medicine and Dentistry, Queen Mary University of London
17Ref: P010 A synthetic peptide designed to neutralise lipopolysaccharides attenuates metaflammation and diet-induced metabolic derangements in mice
Guilherme Martins Silva
University of São Paulo
Brazil
18Ref: P014 Development of Robust and Predictive Machine Learning QSAR Models for Hepatic Stability
Christopher Southan
TW2Informatics
Sweden
19Ref: P017 Chemical probe assessments for expanding the drug target envelope
Sofie Pattyn
ImmunXperts
Belgium
20In vitro exhausted T cell assay for immuno-oncology candidates
Flavia Messina
University College Dublin
Ireland
21Ref: P002 Evaluation of the neuroprotective mechanism of 7,8-dihydroxyflavone and generation of corresponding sustained release nano/microparticles for improved ocular drug delivery
Sebastian Schloer
University of Muenster
Germany
22P005 Targeting the endolysosomal host-SARS-CoV-2 interface by the FIASMA fluoxetine and the drug synergy of combinatory treatment with remdesivir
Count: 22