7Developing a high-throughput screening assay to support the drug discovery of γ-aminobutyric acid type A receptor (GABAAR) Positive Allosteric Modulators, for the treatment of Post-Partum Depression.
12Development of a high-throughput quantitative biochemical ubiquitination assay platform to support E3 ligase recruitment and modulation drug discovery programmes
17Synthesis, antimicrobial and computational studies of natural products derivatives of tricarbonyl (2-methoxycyclohexadienyl)iron tetrafluoroborate salt: An alternative route to natural products modification
110P2X7 receptor mediated cytokine release from human microglia (monocyte-derived) and precision-cut brain slices; implications for patients with TBI and other brain pro-inflammatory conditions
142Evaluation of in vitro human alveolar and bronchial microphysiological systems to predict the permeability and absorption of inhaled pulmonary medications.
1443Discovery platform: boosting hit-identification and lead-optimisation efficiency by merging fragment screening, virtual screening, parallel synthesis and chirally pure chemical space
149A sensitive, homogeneous, and high-throughput assay for homologous recombination DNA repair (HRR) modulators using the engineered luminescent enzyme
154Fast, reproducible and scalable generation of functional microglia from hiPSCs for neuroinflammation and neurodegenerative disease research & drug development
155High-content imaging-based profiling of ion channel gene expression and function in primary cultures of rodent dorsal root ganglion and trigeminal ganglion cells
159Avoid the fear of missing out: Early, thorough assessment of assay translation is crucial in dictating screening strategy and reducing the risk of false negatives
171Evaluating different modalities of drug-induced liver injury using a sensitive and selective human liver microphysiological system and clinical biomarkers
184Development of a multiparametric cardiovascular toxicity assay using iPSC derived cardiomyocytes, endothelial cells, and primary cardiac fibroblasts
