Drug Discovery 2022: driving the next life science revolution

Presentations A to Z

Programme : Presentations A to Z
10x Your Lab: High Content Analysis Meets High-Throughput Screening
Tue4  Oct02:30pm(5 mins)
 Ms Kristin Halfpenny  
Session : High Content Imaging in Drug Discovery
Room: Auditorium 1
Accelerating Drug Discovery with Cell Painting
Tue4  Oct12:10pm(30 mins)
 Mr James Pilling Mr James Pilling  
Session : High Content Imaging in Drug Discovery
Room: Auditorium 1
Advancing UK Medicines Discovery through Innovative Partnerships
Wed5  Oct04:15pm(30 mins)
 Dr Martin Main Dr Martin Main  
Session : Innovation through partnership - Sponsored by AstraZeneca Open Innovation
Room: Auditorium 2
An Educational Approach for Drug Discover Using AI Driven Closed Loop Experimentation
Wed5  Oct02:40pm(30 mins)
 Dr Joshua Kangas Dr Joshua Kangas  
Session : Advancements in Screening and Automation Sponsored by IDBS
Room: Auditorium 3
Armouring CAR-T cells therapy against the immunosuppressive microenvironment in solid tumour
Tue4  Oct02:40pm(30 mins)
 Dr Romain Lara Dr Romain Lara  
Session : Cell & Gene Therapy Sponsored by Miltenyi
Room: Auditorium 3
Assist Plus Pipetting Platform
Tue4  Oct02:30pm(5 mins)
 Ms Sharon Barnard  
Session : Cell & Gene Therapy Sponsored by Miltenyi
Room: Auditorium 3
Audience Lead Panel Discussion with Q&A
Tue4  Oct04:30pm(30 mins)
 Dr Allan Jordan Dr Allan Jordan Sarah Skerrat Sarah Skerrat 
Session : Overcoming Challenges and New Directions in Medicinal Chemistry
Room: Auditorium 2
Automated analysis workflow to identify metal contamination in HTS outputs
Wed5  Oct11:35am(30 mins)
 Dr Rachel Moore Dr Rachel Moore  
Session : Advancements in Screening and Automation Sponsored by IDBS
Room: Auditorium 3
Automating high-throughput NGS and qPCR assays: Meet the Biomark™ X and the Juno™
Tue4  Oct12:40pm(5 mins)
 James Curtis James Curtis  
Session : Cell & Gene Therapy Sponsored by Miltenyi
Room: Auditorium 3
Beyond Small Molecules…
Wed5  Oct12:35pm(15 mins)
 David Madge  
Session : Innovation through partnership - Sponsored by AstraZeneca Open Innovation
Room: Auditorium 2
Bioluminescent assay tools for TCR-T and CAR-T development and characterisation
Tue4  Oct02:35pm(5 mins)
 Dr Craig Malcolm  
Session : Cell & Gene Therapy Sponsored by Miltenyi
Room: Auditorium 3
Biomarker Discovery Using Preclinical Models: Resources, Challenges and Opportunities
Wed5  Oct11:05am(30 mins)
 Youtube Dr Benjamin Haibe-Kains Dr Benjamin Haibe-Kains  
Session : Developments in Preclinical Models
Room: Auditorium 1
Building a Strong Digital Foundation to Accelerate Innovation and Drug Discovery
Wed5  Oct02:35pm(5 mins)
 Oliver Pentinmaki  
Session : Innovation through partnership - Sponsored by AstraZeneca Open Innovation
Room: Auditorium 2
Collaborative AMR Implementation in Biopharmaceutical Labs
Wed5  Oct02:00pm(30 mins)
 Mr Thomas Albanetti  
Session : Advancements in Screening and Automation Sponsored by IDBS
Room: Auditorium 3
Cost Effective Decapping
Wed5  Oct02:35pm(5 mins)
 Mr Adam McGinnis  
Session : Advancements in Screening and Automation Sponsored by IDBS
Room: Auditorium 3
Dementia Drugs through Partnership at the ALBORADA Drug Discovery Institute
Wed5  Oct02:40pm(30 mins)
 Dr John Skidmore Dr John Skidmore  
Session : Innovation through partnership - Sponsored by AstraZeneca Open Innovation
Room: Auditorium 2
Developing strategic partnerships to accelerate worldwide access to human cells
Wed5  Oct11:35am(30 mins)
 Kam Dhaliwal David Fischer 
Session : Innovation through partnership - Sponsored by AstraZeneca Open Innovation
Room: Auditorium 2
Developments in Cytometry Technology to Enhance Pre-Clinical Workflows: StarBright Dyes and the ZE5 Cell Analyzer
Wed5  Oct11:35am(30 mins)
 Youtube Dr Richard Cuthbert Dr Richard Cuthbert  
Session : Developments in Preclinical Models
Room: Auditorium 1
Discovery and Development of Pyrukynd®:  The First-in-Class Pyruvate Kinase Activator For The Treatment of Hemolytic Anemia
Wed5  Oct03:45pm(30 mins)
 Dr Lenny Dang Dr Lenny Dang  
Session : Frontiers of chemistry applied to drug discovery
Room: Auditorium 4
Discovery and validation of in vitro and in vivo probes for human DNA Polymerase theta (Polθ)
Tue4  Oct11:10am(30 mins)
 Dr Robert Heald Dr Robert Heald  
Session : Overcoming Challenges and New Directions in Medicinal Chemistry
Room: Auditorium 2
Discovery of the clinical candidate, ASTX029, a dual mechanism ERK inhibitor
Wed5  Oct02:00pm(30 mins)
 Dr Nicola Wallis Dr Nicola Wallis  
Session : Frontiers of chemistry applied to drug discovery
Room: Auditorium 4
Early Career Professional Introduction
Wed5  Oct09:50am(5 mins)
 Dr Mark Soave  
Session : ELRIG - Early Career Professional Impact Award - Supported by Elemental Machines
Room: Auditorium 1
Early experimental medicine studies for investigating new drugs for COPD
Tue4  Oct03:45pm(30 mins)
 Prof Dave Singh Prof Dave Singh  
Session : Drug Discovery and Development in COPD
Room: Auditorium 4
Efficient low-priced custom automation at Abbvie
Wed5  Oct11:05am(30 mins)
 Mario Richter Mario Richter  
Session : Advancements in Screening and Automation Sponsored by IDBS
Room: Auditorium 3
Enhancing the lead discovery assay value chain by an orchestrated lab automation ecosystem
Wed5  Oct03:45pm(30 mins)
 Kirsten Tschapalda Kirsten Tschapalda Dr Federica Morandi 
Session : Advancements in Screening and Automation Sponsored by IDBS
Room: Auditorium 3
Flow Induced Dispersion Analysis (FIDA) Protein QC: Linking absolute hydrodynamic radius determination to structural insight.
Wed5  Oct02:30pm(5 mins)
 Mrs Joanne Walter  
Session : Frontiers of chemistry applied to drug discovery
Room: Auditorium 4
From HTS Campaign to Biophysical Characterization: The Art of Generating Promising Hit Series for PIM3 Kinase
Wed5  Oct02:35pm(5 mins)
 Youtube Dr Celine Legros Dr Celine Legros  
Session : Developments in Preclinical Models
Room: Auditorium 1
From Stem-Cells to T-Cells: Next-Generation DNA NanoVectors -an Alternative Non-Integrating DNA Vector Platform for Regenerative Medicine and Immunotherapy
Tue4  Oct12:10pm(30 mins)
 Dr Richard Harbottle Dr Richard Harbottle  
Session : Cell & Gene Therapy Sponsored by Miltenyi
Room: Auditorium 3
Generating improved preclinical models for profiling novel combinations
Wed5  Oct03:45pm(30 mins)
 Youtube Ms Elizabeth Hardaker Ms Elizabeth Hardaker  
Session : Developments in Preclinical Models
Room: Auditorium 1
Genomic Sciences in Immunology – Strategies for Finding Future Drug Targets through Genetics, Functional Genomics and Immunophenotyping
Wed5  Oct09:05am(45 mins)
 Youtube Rabinder Prinjha Rabinder Prinjha  
Session : Keynote Presentation
Room: Auditorium 1
Green Chemistry at GSK - How and when to use guides, and using Green Chemistry to design a scalable route to a first-in-class BET BD2 inhibitor
Wed5  Oct11:35am(30 mins)
 Mrs Catherine Alder Mrs Catherine Alder  
Session : Frontiers of chemistry applied to drug discovery
Room: Auditorium 4
High Content Imaging as an enabling tool for early drug discovery
Tue4  Oct11:10am(30 mins)
 Dr John Bassett Dr John Bassett  
Session : High Content Imaging in Drug Discovery
Room: Auditorium 1
High Throughput Affinity Screening for Rapid Hit Discovery and Prosecuting Challenging Targets
Wed5  Oct04:15pm(30 mins)
 Miss Poppy Llowarch  
Session : Advancements in Screening and Automation Sponsored by IDBS
Room: Auditorium 3
HTS Assay detection at its best! - New PHERAstar FSX features improve data quality and sample processing
Wed5  Oct02:30pm(5 mins)
 Catherine Wark Catherine Wark  
Session : Advancements in Screening and Automation Sponsored by IDBS
Room: Auditorium 3
Image-based drug screening in patient biopsies for personalized systems medicine and drug discovery
Wed5  Oct04:15pm(30 mins)
 Youtube Prof Berend Snijder Prof Berend Snijder  
Session : Developments in Preclinical Models
Room: Auditorium 1
iPSC automation platform
Wed5  Oct12:05pm(30 mins)
 Dr Martine Geraerts Dr Martine Geraerts  
Session : Advancements in Screening and Automation Sponsored by IDBS
Room: Auditorium 3
KQ Labs accelerator for data driven health start-ups: why does it exist, what does it do and what difference does it make?
Wed5  Oct11:05am(30 mins)
 Dr Barbara Domayne-Hayman Dr Barbara Domayne-Hayman Dr Jelena Aleksic Dr Jelena Aleksic 
Session : Innovation through partnership - Sponsored by AstraZeneca Open Innovation
Room: Auditorium 2
Life beyond the pixels: single-cell analysis using deep learning and image analysis methods
Tue4  Oct02:40pm(30 mins)
 Dr Peter Horvath Dr Peter Horvath  
Session : High Content Imaging in Drug Discovery
Room: Auditorium 1
Ligand discovery in dark chemical space leading to biological insights
Wed5  Oct12:05pm(30 mins)
 Dr John Irwin Dr John Irwin  
Session : Frontiers of chemistry applied to drug discovery
Room: Auditorium 4
Magnetic Electrospun Microfibre Scaffold Assemblies: Examples of there use for Cell-Based Screening Applications
Tue4  Oct04:15pm(15 mins)
 Gary Allenby Gary Allenby  
Session : High Content Imaging in Drug Discovery
Room: Auditorium 1
Methods to tackle novel molecular targets involved in inflammatory disease
Tue4  Oct04:15pm(15 mins)
 Dr Mark Abbott  
Session : Drug Discovery and Development in COPD
Room: Auditorium 4
Microplate readers and imaging systems
Tue4  Oct12:40pm(5 mins)
 Imran Haneef  
Session : High Content Imaging in Drug Discovery
Room: Auditorium 1
ML/AI:  Opportunities, Impact and Future Directions in Drug Design
Tue4  Oct12:10pm(30 mins)
 Sarah Skerrat Sarah Skerrat  
Session : Overcoming Challenges and New Directions in Medicinal Chemistry
Room: Auditorium 2
Morphological trajectory inference: Tracking cell state transitions and the impact of small-molecule perturbations
Tue4  Oct03:45pm(30 mins)
 Dr Rebecca Hughes Dr Rebecca Hughes  
Session : High Content Imaging in Drug Discovery
Room: Auditorium 1
Multiparametric drug discovery facilitated by automated liquid handling
Wed5  Oct12:35pm(15 mins)
 Mark Graham Mark Graham  
Session : Advancements in Screening and Automation Sponsored by IDBS
Room: Auditorium 3
Navigate Your Chemistry And Explore The Biology - Case Studies Of CETSA® overcoming challenges in Drug Discovery
Tue4  Oct04:15pm(15 mins)
 Isabel Martin Caballero Isabel Martin Caballero  
Session : Overcoming Challenges and New Directions in Medicinal Chemistry
Room: Auditorium 2
New Approaches to the Synthesis and Application of DNA-Encoded Libraries
Tue4  Oct02:35pm(30 mins)
 Miss Jessica Graham Miss Jessica Graham Dr Harriet Stanway-Gordon Dr Harriet Stanway-Gordon 
Session : Overcoming Challenges and New Directions in Medicinal Chemistry
Room: Auditorium 2
New perspectives for modelling inflammatory diseases using patient-derived organoids
Tue4  Oct12:10pm(5 mins)
 Dr Sylvia F. Boj Dr Sylvia F. Boj  
Session : Drug Discovery and Development in COPD
Room: Auditorium 4
New technologies for the design and characterisation of nanotechnology mediated therapeutics
Tue4  Oct09:35am(45 mins)
 Prof Molly Stevens Prof Molly Stevens  
Session : Keynote Presentation
Room: Auditorium 1
New/Novel/Ground-breaking technologies assisting the sustainable preclinical drug discovery
Wed5  Oct02:30pm(5 mins)
 Youtube Dr Karthi Rajamani Dr Karthi Rajamani  
Session : Developments in Preclinical Models
Room: Auditorium 1
Next Generation Platforms for Human Gene Therapy
Tue4  Oct04:30pm(30 mins)
 Prof Aravind Asokan Prof Aravind Asokan  
Session : Cell & Gene Therapy Sponsored by Miltenyi
Room: Auditorium 3
Novel drug targets in COPD
Tue4  Oct11:40am(30 mins)
 Prof Ian Adcock Prof Ian Adcock  
Session : Drug Discovery and Development in COPD
Room: Auditorium 4
Optimising proteolysis-targeting chimeras (PROTACs) for oral drug delivery - Design tips and tricks
Tue4  Oct02:00pm(30 mins)
 Dr Jamie Scott Dr Jamie Scott  
Session : Overcoming Challenges and New Directions in Medicinal Chemistry
Room: Auditorium 2
Organoid Biobanks for Cancer Drug Discovery
Wed5  Oct02:00pm(30 mins)
 Youtube Dr Mathew Garnett Dr Mathew Garnett  
Session : Developments in Preclinical Models
Room: Auditorium 1
Oxford Nanopore Technologies - a look into the complete genome
Wed5  Oct12:35pm(15 mins)
 Mr Daniel Fordham Mr Daniel Fordham  
Session : Frontiers of chemistry applied to drug discovery
Room: Auditorium 4
Pandemic response: accessible BSL3 platforms for drug discovery
Wed5  Oct09:55am(20 mins)
 Youtube Dr Shaun Pennington Dr Shaun Pennington  
Session : ELRIG - Early Career Professional Impact Award - Supported by Elemental Machines
Room: Auditorium 1
Patient-Derived Cell (PDC) Models as a Tool to Assess Cancer Therapeutic Efficacy Across the Drug Development Life Cycle
Tue4  Oct11:40am(30 mins)
 Dr Rachel Howard-Jones Dr Rachel Howard-Jones  
Session : High Content Imaging in Drug Discovery
Room: Auditorium 1
Phenonaut; a tool for multiomic data integration, analysis, prediction, and inference
Tue4  Oct02:00pm(30 mins)
 Dr Steven Shave Dr Steven Shave  
Session : High Content Imaging in Drug Discovery
Room: Auditorium 1
Pin-point™ – A Modular Base Editing System Driving Cell and Gene therapies
Tue4  Oct02:00pm(30 mins)
 Dr Michael Anbar Dr Michael Anbar  
Session : Cell & Gene Therapy Sponsored by Miltenyi
Room: Auditorium 3
Platforms for the generation and high-throughput screening of cyclic peptide libraries.
Wed5  Oct11:05am(30 mins)
 Prof Ali Tavassoli Prof Ali Tavassoli  
Session : Frontiers of chemistry applied to drug discovery
Room: Auditorium 4
Preclinical translational models for investigating drugs for the treatment of COPD
Tue4  Oct02:00pm(30 mins)
 Dr Simon Pitchford Dr Simon Pitchford  
Session : Drug Discovery and Development in COPD
Room: Auditorium 4
Pressure over liquid – Established technology but with new value
Wed5  Oct02:30pm(5 mins)
 Paul Kendall Paul Kendall  
Session : Innovation through partnership - Sponsored by AstraZeneca Open Innovation
Room: Auditorium 2
Publishing in the British Journal of Pharmacology
Tue4  Oct04:30pm(30 mins)
 Mr Charles Whalley  
Session : Drug Discovery and Development in COPD
Room: Auditorium 4
Quantitative high-throughput screening of single cancer cell phenotypes in 3D matrices
Tue4  Oct04:30pm(30 mins)
 Ms Vicky Bousgouni  
Session : High Content Imaging in Drug Discovery
Room: Auditorium 1
Session Introduction
Wed5  Oct11:00am(5 mins)
 Dr Lisa Mohamet Dr Lisa Mohamet Dr Samantha Barichievy Dr Samantha Barichievy 
Session : Developments in Preclinical Models
Room: Auditorium 1
Session Introduction
Tue4  Oct11:05am(5 mins)
 Dr Allan Jordan Dr Allan Jordan Sarah Skerrat Sarah Skerrat 
Session : Overcoming Challenges and New Directions in Medicinal Chemistry
Room: Auditorium 2
Session Introduction
Tue4  Oct11:05am(5 mins)
 Ms Sian Lewis Ms Sian Lewis Dr Michael Howell Dr Michael Howell 
Session : High Content Imaging in Drug Discovery
Room: Auditorium 1
Session Introduction
Wed5  Oct11:00am(5 mins)
 Dr Kathryn Chapman Dr Kathryn Chapman David Powell David Powell 
Session : Innovation through partnership - Sponsored by AstraZeneca Open Innovation
Room: Auditorium 2
Session Introduction
Tue4  Oct11:05am(5 mins)
 Chris Herring Chris Herring Claire Dobson Claire Dobson 
Session : Cell & Gene Therapy Sponsored by Miltenyi
Room: Auditorium 3
Session Introduction
Wed5  Oct11:00am(5 mins)
 Martin Swarbrick Martin Swarbrick Dr Mary Wheldon Dr Mary Wheldon 
Prof A Ganesan Prof A Ganesan Mrs Becky Garton Mrs Becky Garton
Session : Frontiers of chemistry applied to drug discovery
Room: Auditorium 4
Session Introduction
Tue4  Oct11:05am(5 mins)
 Dr Anna Morgan Dr Anna Morgan Dr Simon Pitchford Dr Simon Pitchford 
Session : Drug Discovery and Development in COPD
Room: Auditorium 4
Session Introduction
Wed5  Oct11:00am(5 mins)
 Mario Richter Mario Richter Kirsten Tschapalda Kirsten Tschapalda 
Session : Advancements in Screening and Automation Sponsored by IDBS
Room: Auditorium 3
Simplifying Synthesis with Electricity
Wed5  Oct04:15pm(45 mins)
 Prof Phil Baran Prof Phil Baran  
Session : Frontiers of chemistry applied to drug discovery
Room: Auditorium 4
spheroONE – an automated high throughput spheroid isolation and manipulation technology.
Tue4  Oct02:35pm(5 mins)
 Alice Cheesbrough Alice Cheesbrough  
Session : High Content Imaging in Drug Discovery
Room: Auditorium 1
Supporting innovations in Splicesome research
Tue4  Oct02:30pm(5 mins)
 Mrs ROSLYN McConnell  
Session : Overcoming Challenges and New Directions in Medicinal Chemistry
Room: Auditorium 2
Targeting the template: A novel therapeutic strategy for prion diseases
Tue4  Oct03:45pm(30 mins)
 Dr Heulyn Jones Dr Heulyn Jones  
Session : Overcoming Challenges and New Directions in Medicinal Chemistry
Room: Auditorium 2
TargetMol：Targets small molecules in drug discovery
Wed5  Oct02:35pm(5 mins)
 Ms Phoebe Feng  
Session : Frontiers of chemistry applied to drug discovery
Room: Auditorium 4
TCR Evolution, revolution: How Adaptimmune is developing innovative TCR T-cell therapies to treat solid tumors
Tue4  Oct11:10am(30 mins)
 Dr Jo Brewer Dr Jo Brewer  
Session : Cell & Gene Therapy Sponsored by Miltenyi
Room: Auditorium 3
The benefits of working side-by-side: The Crick-GSK Biomedical LinkLabs collaboration.
Wed5  Oct03:45pm(30 mins)
 Dr Katrin Rittinger Dr Katrin Rittinger Dr Andrew Powell Dr Andrew Powell 
Session : Innovation through partnership - Sponsored by AstraZeneca Open Innovation
Room: Auditorium 2
The burden of unmet needs in COPD
Tue4  Oct11:10am(30 mins)
 Prof Wisia Wedzicha Prof Wisia Wedzicha  
Session : Drug Discovery and Development in COPD
Room: Auditorium 4
The COVID Moonshot – from open science collaboration in fragment screening to drug candidate and beyond to Pandemic Preparedness
Tue4  Oct11:40am(30 mins)
 Dr Ed Griffen Dr Ed Griffen  
Session : Overcoming Challenges and New Directions in Medicinal Chemistry
Room: Auditorium 2
The Discovery and Clinical Efficacy of Sisunatovir
Wed5  Oct02:40pm(30 mins)
 Dr Stuart Cockerill Dr Stuart Cockerill  
Session : Frontiers of chemistry applied to drug discovery
Room: Auditorium 4
The Drug Discovery Unit: Leading the development of new anti-infective treatments with a collaborative approach
Wed5  Oct02:00pm(30 mins)
 Dr Beatriz Baragana Dr Beatriz Baragana  
Session : Innovation through partnership - Sponsored by AstraZeneca Open Innovation
Room: Auditorium 2
The impact of not understanding the genetic landscape, Ignorance will cost you time and money.
Tue4  Oct04:15pm(15 mins)
 Melanie Maerken  
Session : Cell & Gene Therapy Sponsored by Miltenyi
Room: Auditorium 3
The Joint AstraZeneca-Cancer Research Horizon Functional Genomics Centre (FGC): A partnership demonstrating how together we innovate faster and impact more
Wed5  Oct12:05pm(30 mins)
 Dr Douglas Ross-Thriepland Dr Douglas Ross-Thriepland  
Session : Innovation through partnership - Sponsored by AstraZeneca Open Innovation
Room: Auditorium 2
The journey from discovery to therapy begins with a single cell
Tue4  Oct11:40am(30 mins)
 Stephen Hague  
Session : Cell & Gene Therapy Sponsored by Miltenyi
Room: Auditorium 3
Unlocking a revolutionary class of in vivo reprogramming therapies through systematic, unbiased identification of the key cell switches controlling cell fate
Tue4  Oct03:45pm(30 mins)
 Dr Louise Modis Dr Louise Modis  
Session : Cell & Gene Therapy Sponsored by Miltenyi
Room: Auditorium 3
Upgrading African disease-in-a-dish models for pharmacovigilance: Enter the humble cell
Wed5  Oct02:40pm(30 mins)
 Youtube Dr Janine Scholefield Dr Janine Scholefield  
Session : Developments in Preclinical Models
Room: Auditorium 1
Use of human tissues to investigate drugs for the treatment of COPD
Tue4  Oct02:30pm(30 mins)
 Prof Luigino Calzetta Prof Luigino Calzetta  
Session : Drug Discovery and Development in COPD
Room: Auditorium 4
Use of Imaging for preclinical evaluation of drugs for the treatment of COPD
Tue4  Oct12:15pm(30 mins)
 Dr Anna Morgan Dr Anna Morgan  
Session : Drug Discovery and Development in COPD
Room: Auditorium 4
Using human iPSC technology to model disease-relevant signatures of Alzheimer's disease and other tauopathies
Wed5  Oct12:35pm(15 mins)
 Youtube Dr Laura Calo Dr Laura Calo  
Session : Developments in Preclinical Models
Room: Auditorium 1
Utilising complex in vitro gut models in drug discovery: they needn’t be hard to stomach
Wed5  Oct12:05pm(30 mins)
 Youtube Mr Nathaniel Lam Mr Nathaniel Lam  
Session : Developments in Preclinical Models
Room: Auditorium 1

Programme

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