Research & Innovation 2015 - Accelerating Early Discovery
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Presentation
Wed 18 March
DAY 1F7F1G4Exhibit HallDAY 1
DAY 1F7F1G4Exhibit HallDAY 1
8:00 Arrival, Registration & Coffee 8:00:
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9:00 9:00:
9:05: Opening Remarks & Introduction of Keynote Speaker
09:05 (10 mins)
Mike Jowett, Horizon Discovery  
9:05:
9:10: 9:10:
9:15: Open Innovation for Sustainable Medicines R&D
09:15 (60 mins)
Mark Bamford, GlaxoSmithKline  
9:15:
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10:00 10:00
10:05 10:05
10:10 10:10
10:15 Coffee Break 10:15
10:20 10:20
10:25 10:25
10:30 10:30
10:35 10:35
10:40 10:40
10:45 Session Chair Introductions
10:45 (10 mins)
Malcolm Haddrick, AstraZeneca  
Session Chair Introductions
10:45 (10 mins)
Vinoj George, Centre for Biomolecular Sciences (CBS), University of Nottingham  
Session Chair Introductions
10:45 (10 mins)
Ian Waddell , Cancer Research UK  
10:45
10:50 10:50
10:55 Epigenetic "Mutagens": Do They Exist? How Might We Identify Them?
10:55 (30 mins)
Richard M Walmsley, Gentronix Ltd - Uni.Manchester  
Are All iPSC-Derived Cardiomyocytes Electrically Equal?
10:55 (30 mins)
Godfrey Smith, Clyde Bioscience  
The Only Way Is… Open Access - Generating Affordable and Pioneer Treatments for Chronic and Rare Diseases
10:55 (30 mins)
Wen Hwa Lee, Structural Genomics Consortium, University of Oxford   
10:55
11:00 11:00
11:05 11:05
11:10 11:10
11:15 11:15
11:20 11:20
11:25 Use of Human Liver Microtissues for Drug Safety Assessment
11:25 (30 mins)
Dominic Williams, Astrazeneca Cambridge  
A Novel Approach to Functional Screening of Neuronal Excitability and Plasticity in Primary Neurons
11:25 (30 mins)
Paul Karila , Cellectricon  
Edinburgh Cancer Discovery Unit (ECDU) and Edinburgh Phenotypic Assay Development Centre (E-PAD): Building Synergistic Alliances with Industry
11:25 (30 mins)
Neil Carragher, University of Edinburgh  
11:25
11:30 11:30
11:35 11:35
11:40 11:40
11:45 11:45
11:50 11:50
11:55 Screening for Cell Death - A Comparison of Methods
11:55 (15 mins)
Lisa McWilliams, AstraZeneca  
Inhibition of SMARCA2: a Novel Target for SMARCA4-Deficient Lung Adenocarcinoma
11:55 (15 mins)
Nikki March, Cancer Research UK Manchester Institute  
Development of a High-Content Platform to Characterise Large Numbers of Induced Pluripotent Stem Cell Lines
11:55 (15 mins)
Natalie Moens, Centre for Stem Cells and Regenerative Medicine, King's College London  
11:55
12:00 12:00
12:05 12:05
12:10 High Efficiency Differentiation and Maturation of Human Pluripotent Stem Cell (hPSC)-derived Cardiomyocytes
12:10 (15 mins)
Minh Duc Hoang , University of Nottingham  
Co-Culture Spheroids for Phenotypic Preclinical Assessment of Direct Drug Delivery to Pediatric Brain Tumours
12:10 (15 mins)
Deylan Ivanov, University of Nottingham  
12:10
12:15 12:15
12:20 12:20
12:25 DRAQ7™: Far-Red Real-Time Viability Monitoring, Cell-by-Cell
12:25 (5 mins)
Roy Edward, BioStatus Limited  
An Automated Approach to High Content Screening
12:25 (5 mins)
David Ley, Peak Analysis & Automation  
RFID... The way Forward in Cryo-Storage
12:25 (5 mins)
Colin Thorne, Cryogatt  
12:25
12:30 Cell Viability Assessment in 3D Cultures With CellTiter-Glo® 3D Cell Viability Assay Reagent
12:30 (5 mins)
Craig Malcolm, Promega  
Cytation™ 5 Cell Imaging Multi-Mode Microplate Reader: An Overview
12:30 (5 mins)
Lindsay Wood, BioTek Instruments  
Open Innovation with Sygnature Discovery
12:30 (5 mins)
Lyn Parkinson, Sygnature Discovery  
12:30
12:35 LabLogic Introduces the Hidex Sense Multi-Technology Microplate Reader – Performance at your Fingertips
12:35 (5 mins)
Anna Groom, LabLogic  
Maximising Data Generation From Every Cell Imaging Experiment
12:35 (5 mins)
Jonathan Sheard, CM Technologies Oy   
LightSwitch™ Custom Services : Gene Regulation Services to Help Accelerate Your Research
12:35 (5 mins)
Priya Karan, Active Motif  
12:35
12:40 Using Impedance-Based Approaches for Measuring Cell-Mediated Cytotoxicity and Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC)
12:40 (5 mins)
Jay Champaneri , Cambridge Bioscience  
VIAFLO ASSIST – Your Personal Pipetting Assistant
12:40 (5 mins)
Sharon Barnard , Integra   
TBD
12:40 (5 mins)
Rachel Shuker, DiscoveRx  
12:40
12:45 The CLARIOstar - Offering Flexibility & Sensitivity
12:45 (5 mins)
Catherine Wark, BMG Labtech  
Celigo S Imaging Cytometer for 2D and 3D ImmunoOncology Research
12:45 (5 mins)
Scott Cribbes, Nexcelom BioScience Ltd  
BlueCatBio BlueWasher: Contact-Free, Near Zero Residual Volume Microplate Washing and Media Changes
12:45 (5 mins)
Kerstin Hagen-Mann , BlueCatBio  
12:45
12:50 12:50
12:55 Lunch - Exhibition - Posters 12:55
1:00 1:00:
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2:00 Towards a New Paradigm in Genetic Toxicology: From Qualitative to Quantitative Approaches
14:00 (30 mins)
George Johnson, Swansea University  
Generation of Human Cellular Models for Drug Screening Using CRISPR/Cas9 Technology
14:00 (30 mins)
Viola Borgdorff, University of Nottingham  
Drug Discovery in an Academic Setting - the Best of Both Worlds?
14:00 (30 mins)
Simon Ridley, Alzheimer’s Research UK  
2:00:
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2:30: In Vitro Generation of Functional Organoid Structures Resembling Embryonic Liver Buds Using Differentiated Human Cells
14:30 (30 mins)
Katja Breitkopf-Heinlein, University of Heidelberg  
Developing Novel Biomaterials-Based Platforms for Translational Applications
14:30 (30 mins)
Lesley Chow, Imperial College London  
New Ways to Fund Early Stage Drug Discovery and Development From an Early Stage Investor's Perspective
14:30 (30 mins)
Robert James, Sixth Element Capital  
2:30:
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3:00 Novel Methods to Measure Cell Viability in Real Time Enables Multiplexing Opportunities
15:00 (30 mins)
Terry Riss, Promega Corporation  
Innovative Use of Scaffolding Materials to Support 3D Cell Growth and Build Improved In Vitro Assays
15:00 (30 mins)
Stefan Przyborski, CSO, Reinnervate Limited  
Open innovation in practice: An Automated High Throughput Imaging Screen for the Identification of Anti-Wolbachia Agents
15:00 (30 mins)
Rachel Clare, Liverpool School of Tropical Medicine (LSTM)  
3:00:
3:05: 3:05:
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3:30: Coffee Break 3:30:
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4:00 Automation Platforms for Stem Cells and Heart Disease
16:00 (30 mins)
Chris Denning, Wolfson Centre for Stem Cells, Tissue Engineering & Modelling (STEM), University of Nottingham  
Profiling Compounds in Primary Human Cell BioMAP® Systems For Drug Discovery and Therapeutic Development in Inflammation and Cancer
16:00 (30 mins)
Andrew Baxter, DiscoveRx Corporation  
Nothing Ventured Nothing Gained: Supporting Innovation via Novel Venture Collaborations
16:00 (30 mins)
Ashwani Bahl, Eli Lilly and Company  
4:00:
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4:30: Advanced In Vitro Models: The Future of Early Cardiovascular Safety Testing?
16:30 (30 mins)
Chris Pollard, AstraZeneca  
Novel Assays for Immuno-Oncology Using Kinetic Live Cell Imaging
16:30 (30 mins)
Nicola Bevan, Essen Bioscience  
Drug Discovery Through Academic/Industry Collaboration
16:30 (30 mins)
Allan Jordan, CRUK Manchester Institute  
4:30:
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5:00 Close of Conference 5:00:
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