BSP Spring Meeting 2018

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DAY 2

Great Hall, Arts Centre

Stream 1 - Edward Llwyd 0.26 Biology Main

Stream 2 - Llandinam A6

Stream 3 - Physics 0.15 Main

Stream 4 - Edward Llwyd 0.01

DAY 2

Stream 5 - IBERS 0.33 (Monday), Physisc 0.11 (Tuesday & Wednesday)

Students Union Building

DAY 4

8:00

Registration

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9:00

Tryps & Leish Cell & Molecular Biology II

Chairs: Wendy Gibson, University of Bristol

Stream 1 - Edward Llwyd 0.26 Biology Main

Post-transcriptional regulation of the Trypanosoma brucei cell cycle
09:00 (30 mins)
Keynote Speaker: Michael Urbaniak, Lancaster University

In Vitro Characterization of a compound capable of arresting T. Cruzi cell cycle without affecting parasite viability
09:30 (15 mins)
Adalberto Miguel de Araújo Júnior, Federal University of São Paulo

Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1
09:45 (15 mins)
Sam Alsford, London School of Hygiene and Tropical Medicine

Chemical-mediated transfection meets Parasitology: Trypanosomatids as proof-of-concept for the technology
10:00 (15 mins)
Francisco Olmo, London School of Hygiene and Tropical Medicine

ERAD and disposal of misfolded GPI-anchored proteins in Trypanosoma brucei
10:15 (15 mins)
Calvin Tiengwe, SUNY Buffalo

Public Engagement with Science

Chairs: Jo Hamilton, Institute of Biological Sciences Helen Price, Keele University

Stream 2 - Llandinam A6

From Parasites to Public Engagement and Impact
09:00 (30 mins)
Keynote Speaker: Sheena Cruickshank, University of Manchester

Ticks: getting the bite right
09:30 (30 mins)
Richard Wall, University of Bristol

The challenge of Malaria
10:00 (30 mins)
Paul Horrocks, Institute for Science and Technology in Medicine

Helminths: Immuno-modulation

Chairs: Alex Loukas, James Cook University

Stream 3 - Physics 0.15 Main

Helminths and other environmental factors shaping the immune response: consequences
09:00 (30 mins)
Keynote Speaker: Maria Yazdanbakhsh, Leiden University Medical Center

Antigenic cross-reactivity between Schistosoma mansoni and allergens: a possible alternative explanation for the hygiene hypothesis
09:30 (15 mins)
Keynote Speaker: Mike Doenhoff, University of Nottingham

Unravelling early host intestinal epithelia interactions with whipworms using intestinal organoids
09:45 (15 mins)
Maria Adelaida Duque-Correa, Wellcome Sanger Institute

Antigenic targets of IgG1-associated anti-fecundity immunity against Schistosoma haematobium
10:00 (15 mins)
Rebecca Oettle, University of Cambridge

Infection-state independent moderation of Th2 inflammation and inflammatory-associated lymphatic remodelling by tetracyclines in pre-clinical lymphatic filariasis pathology models
10:15 (15 mins)
Stephen Cross, Liverpool school of tropical medicine

Ecological Parasitology II

Chairs: Katie O'Dwyer, Home

Stream 4 - Edward Llwyd 0.01

The world in an oyster - biological invasions and their impact on parasite-host interactions
09:00 (30 mins)
Keynote Speaker: David Thieltges, NIOZ Royal Netherlands Institute for Sea Research

The role of the urban environment in shaping parasite communities of red foxes in Edinburgh
09:30 (15 mins)
Lisa Gecchele, The University of Edinburgh

Ecological and population-level drivers of gastrointestinal parasitism in the Genus Papio: a meta-analysis
09:45 (15 mins)
Cassandra Raby, University of Liverpool

Parasite-mediated effects of an invasive fish on native brown trout
10:00 (15 mins)
Paula Tierney, Zoology Department, Trinity College

Infected crayfish play it safe: Aphanomyces astaci reduces crayfish movement on land
10:15 (15 mins)
Rhidian Thomas, Cardiff University

9:00

Veterinary Parasitology - Diagnostics & Therapeutics Sponsor - Techion

Chairs: John Ellis, University of Technology Sydney Justin Pachebat, IBERS, Aberystwyth University

Stream 5 - IBERS 0.33 (Monday), Physisc 0.11 (Tuesday & Wednesday)

Current innovations in parasite diagnostics – what does the future look like?
09:00 (30 mins)
Keynote Speaker: Greg Mirams, Techion Group Ltd

Molecular detection of fancy birds parasites for clinical diagnosis and epidemiology
09:30 (15 mins)
Muhammad Fiaz Qamar, University of Veterinary & Animal Sciences

On the importance of validating diagnostic RT-PCR assays for Dientamoeba fragilis and other gastrointestinal pathogens of human and veterinary importance
09:45 (15 mins)
John Ellis, University of Technology Sydney

Isolation and characterization of novel reagents using phage display technique for detection of pathogenic Acanthamoeba
10:00 (15 mins)
Tim Paget, University of Sunderland

Evaluation of oxfendazole in the treatment of zoonotic Onchocerca lupi infection in dogs
10:15 (15 mins)
Vito Colella, University of Bari

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Coffee Break

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Plenary III

Chairs: Peter Preiser, Nanyang Technological University

Great Hall, Arts Centre

Genetic modification of Plasmodium for malaria vaccine development
11:15 (45 mins)
Keynote Speaker: Shahid Khan, Leiden University Medical Center

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12:00

Plenary IV

Chairs: Peter Preiser, Nanyang Technological University

Great Hall, Arts Centre

Tsetse and trypanosomes
12:00 (45 mins)
Keynote Speaker: Wendy Gibson, University of Bristol

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12:45

Meet the Editors Workshop. NOTE LOCATION: Great Hall
12:45 (75 mins)

12:45

WormBase Training Session: Location: LL Computer Room B23 (100)
12:45 (75 mins)

Lunch Break

12:45

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12:55

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2:00

Host -Vector- Parasite Interactions I

Chairs: Alvaro Acosta-Serrano, Liverpool School of Tropical Medicine

Stream 1 - Edward Llwyd 0.26 Biology Main

The cell cycle and the distinct antioxidant defence mechanisms of Trypanosoma rangeli
14:00 (30 mins)
Keynote Speaker: Edmundo Grisard, Universidade Federal de Santa Catarina

Complementary paths to Chagas disease elimination: the impact of combining vector control with aetiological treatment
14:30 (15 mins)
Maria-Gloria Basanez, Imperial College London, Faculty of Medicine

Parallel sexual and parasexual population genomic structure in Trypanosoma cruzi
14:45 (15 mins)
Philipp Schwabl, University of Glasgow

Revisiting the intracellular cycle of Trypanosoma cruzi in chronically infected animals
15:00 (15 mins)
Martin Taylor, London School of Hygiene and Tropical Medicine

Fatal progression of experimental visceral leishmaniasis is associated with secondary infection by commensal bacteria and severe anaemia.
15:15 (15 mins)
Michael Lewis, London School of Hygiene and Tropical Medicine

Protozoa: Cell Biology & Immunology II - Sponsored by William Powell

Chairs: Miguel Prudencio, IMM Lisboa

Stream 2 - Llandinam A6

Host cell cytosolic immune response during Plasmodium liver stage development
14:00 (30 mins)
Keynote Speaker: Volker Heussler, Bern University

Malaria parasite cycling: in and out of erythrocytes
14:30 (30 mins)
Keynote Speaker: Tony Holder, The Francis Crick Institute

Comparative pathogenicity of Brazilian, Caribbean and European isolates of Toxoplasma gondii
15:00 (15 mins)
Clare Hamilton, Moredun Research Institute

Plasmodium falciparum-infected red blood cells and serum taken from patients with malaria cause pathological alterations in the blood brain barrier
15:15 (15 mins)
Nana Efua Andoh, Keele University

Omics I. Sponsor - WORMBASE Parasite

Chairs: Cornelis Hokke, Leiden University Medical Center

Stream 3 - Physics 0.15 Main

‘Drugging’ Liver Fluke into the 21st Century
14:00 (30 mins)
Keynote Speaker: Aaron Maule — WormBase ParaSite

G protein-coupled receptors (GPCRs) in the liver fluke, Fasciola hepatica
14:30 (15 mins)
Paul McVeigh, Queen's University Belfast

Determining anti-glycan antibody responses to Haemonchus contortus Barbervax vaccine using glycan array screening.
14:45 (15 mins)
Eve Hanks, University of Glasgow

Chromatin structure changes are essential for life cycle progression of the human parasite Schistosoma mansoni
15:00 (15 mins)
Christoph Grunau, UMR5244 University of Perpignan/CNRS

Ecological Parasitology: Molecular Ecology and Evolution of Parasites

Chairs: Joe Jackson, University of Salford

Stream 4 - Edward Llwyd 0.01

Determinants of genetic structure and diversity patterns in parasite population
14:00 (30 mins)
Keynote Speaker: Isabel Blasco-Costa, Natural History Museum of Geneva

Xenomonitoring of schistosomiasis transmission on Pemba Island (Zanzibar)
14:30 (15 mins)
Tom Pennance, Natural History Museum

Totiviruses, parasites and everything else
14:45 (15 mins)
Ahmad Garziz, Bangor Unversity

Parasitic feminisation of crustaceans
15:00 (15 mins)
Joseph Ironside, Aberystwyth University

Patterns of genetic variation in the parasitic nematode Strongyloides ratti.
15:15 (15 mins)
Rebecca Cole, University of Bristol

2:00

Veterinary Parasitology Symposium - Arthropod Ectoparasites and Vectors. Sponsor - MSD Animal Health

Chairs: Richard Wall, University of Bristol

Stream 5 - IBERS 0.33 (Monday), Physisc 0.11 (Tuesday & Wednesday)

Thelazia callipaeda: from oriental to European eyeworm
14:00 (30 mins)
Keynote Speaker: Domenico Otranto, University of Bari

Molecular Epidemiology of Tick-Borne Haemoparasites in Nigerian Sheep
14:30 (15 mins)
Babagana Mohammed Adam, University of Salford

Ecological niche modelling of Phortica variegata and the potential for Thelazia callipaeda introduction to the UK
14:45 (15 mins)
John Graham-Brown, Infection Biology, University of Liverpool

The Prevalence and distribution of Babesia and Borrelia pathogens in ticks infesting domestic dogs in the UK
15:00 (15 mins)
Swaid Abdullah, University of Bristol

Optimisation of an on-hen feeding device for all hematophagous life stages of poultry red mite: a tool for mite control evaluation.
15:15 (15 mins)
Francesca Nunn, Moredun Research Institute

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Coffee Break

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Host -Vector- Parasite Interactions II

Chairs: George Dimopoulos, Johns Hopkins University, Bloomberg School of Public Health

Stream 1 - Edward Llwyd 0.26 Biology Main

A second uninfected blood meal in sand flies promotes reverse metacyclogenesis and Leishmania replication.
16:15 (30 mins)
Keynote Speaker: Jesus Valenzuela, NIAID

The mRNA-bound proteome of Leishmania is stage-regulated with little correlation to transcriptome or whole proteome expression
16:45 (15 mins)
Pegine Walrad, University of York

Differential expression of Vitamin D related genes in Macular vs. Polymorphic Post Kala-azar Dermal Leishmaniasis
17:00 (15 mins)
Srija Moulik, Institute of PG Medical Education and Research

Comparative metabolism of Trypanosoma brucei brucei and the livestock trypanosome T. congolense
17:15 (15 mins)
Pieter Steketee, The Roslin Institute

Curative Benznidazole treatment in the acute stage of Trypanosoma cruzi infection prevents the development of chronic cardiac fibrosis
17:30 (15 mins)
Amanda Francisco, London School of Hygiene and Tropical Medicine

Protozoa: Cell Biology & Immunology III Sponsor -Life Sciences Research Network Wales

Chairs: Volker Heussler, Bern University

Stream 2 - Llandinam A6

Pre-Clinical and Early Clinical Evaluation of a Plasmodium berghei Sporozoite-Based Malaria Vaccine
16:15 (30 mins)
Keynote Speaker: Miguel Prudencio, IMM Lisboa

Differential location and interactions of PfRH1 processing products during merozoite invasion
16:45 (30 mins)
Keynote Speaker: Peter Preiser, Nanyang Technological University

Plasmodium falciparum infected erythrocytes from cerebral malaria cases bind preferentially to brain microvascular endothelium; a study in Malawian children
17:15 (15 mins)
Janet Storm, Liverpool School of Tropical Medicine

IgG and IgE responses to Plasmodium falciparum and intestinal parasites antigens in Mozambican children
17:30 (15 mins)
Rebeca Santano, Barcelona Institute for Global Health

Magnitude of the inflammatory response to parasite infection differentiates calf and adult bovine monocytes
17:45 (15 mins)
Parul Sharma, University of Nottingham

Helminths: Drug Discovery & Resistance II. Sponsored by Life Sciences Research Network Wales.

Chairs: Raymond Pierce, CIIL, Pasteur Institute of Lille

Stream 3 - Physics 0.15 Main

Genetic and molecular basis of triclabendazole resistance in Fasciola hepatica
16:15 (30 mins)
Keynote Speaker: Jane Hodgkinson, UOL

Development of a long-term Brugia malayi lymphatic endothelial cell co-culture system and its validation as an alternative to in vivo screening for anti-Wolbachia drug assessment
16:45 (15 mins)
Amy Marriott, Liverpool School of Tropical Medicine

G-quadruplexes in the parasitic platyhelminth Schistosoma mansoni: identification and anthelmintic drugability
17:15 (15 mins)
Holly Craven, Aberystwyth Univeristy

Anthelmintic action of triclabendazole in vivo in juvenile tropical liver fluke, Fasciola gigantica: a scanning and transmission electron microscope study
17:30 (15 mins)
Ahammed Shareef, PSMO College

The first industrial scale screen of 1.3 million compounds against Wolbachia identifies five promising new leads for the treatment of lymphatic filariasis and onchocerciasis
17:45 (10 mins)
Rachel Clare, LSTM

Ecological Parasitology: Aquatic Parasitology I

Chairs: Sarah Culloty, University College Cork

Stream 4 - Edward Llwyd 0.01

Parasite resistance: from genes to ecosystems
16:15 (30 mins)
Keynote Speaker: Chrisophe Eizaguirre, Queen Mary, University of London

The ecological role of trematode parasites in aquatic food webs: a case study in a subarctic lake
16:45 (15 mins)
Miroslava Soldanova, Biology Centre, Czech Academy of Sciences

Vertical transmission and drivers of myxozoan distributions
17:00 (15 mins)
Paolo Ruggeri, Natural History Museum

The global success of monogeneans: more than just a fluke
17:15 (15 mins)
Jo James, Environment Agency

Rapid test to detect the infection load of the parasite, Anguillicola crassus, in the European eel, Anguilla anguilla.
17:30 (15 mins)
Michele De Noia, glasgow University

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Veterinary Parasitology Symposium - Livestock Parasitology. Sponsor - Ridgeway Research

Chairs: Joanne Webster, Royal Veterinary College

Stream 5 - IBERS 0.33 (Monday), Physisc 0.11 (Tuesday & Wednesday)

Back to the Drawing Board - Basic Science improving Prospects for Control of Liver Fluke in Ruminants
16:15 (30 mins)
Keynote Speaker: Grace Mulcahy, UCD Conway

The impact of acute and chronic infections by parasitic helminths on the faecal microbiota of UK Thoroughbred horses
16:45 (10 mins)
Laura Peachey, University of Cambridge

The clinical importance of Fasciola hepatica infection in horses
16:55 (10 mins)
Alison Howell, University of Liverpool

Neuropeptide Biology in Fasciola hepatica
17:05 (10 mins)
Duncan Wells, QUB

Biomarkers of triclabendazole efficacy against Fasciola hepatica
17:15 (10 mins)
Clare Collett, Aberystwyth University

Examining the presence and function of tuft cells in ovine abomasum tissue following parasitic nematode infection
17:25 (10 mins)
Katie Hildersley, Moredun Research Institute

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Poster Session II & Drinks, Location: Students' Union
17:45 (120 mins)

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Poster Session II & Drinks, Location: Students' Union
17:45 (120 mins)

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8:00

Conference Dinner & Party, Great Hall, Arts Centre

8:00

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