| Thu 30 March |
| Auditorium | The Rosalind Franklin Room | DAY 2 | ||
9:00 | Registration & Coffee | 9:00: | |||
9:05: | 9:05: | ||||
9:10: | 9:10: | ||||
9:15: | 9:15: | ||||
9:20: | 9:20: | ||||
9:25: | 9:25: | ||||
9:30: | Research and Innovation 2023 – Accelerating future drug discovery Chairs: Roger Clark, Charles River Labs Saleha Patel, AstraZeneca Conference Welcome and Keynote Introduction 09:30 (5 mins) Saleha Patel, AstraZeneca Roger Clark, Charles River Labs New perspective on an age-old question 09:35 (45 mins) Ken Raj, Altos Labs Cambridge Institute of Science |
9:30: | |||
9:35: | 9:35: | ||||
9:40: | 9:40: | ||||
9:45: | 9:45: | ||||
9:50: | 9:50: | ||||
9:55: | 9:55: | ||||
10:00 | 10:00 | ||||
10:05 | 10:05 | ||||
10:10 | 10:10 | ||||
10:15 | 10:15 | ||||
10:20 | Early Career Professional Impact Award Chairs: Del Trezise, Sartorius AG Early Career Professional Impact Award Introduction 10:20 (5 mins) Del Trezise, Sartorius AG Early Career Professional Impact Award - Remote and Selective Control of Astrocytes by Magnetomechanical Stimulation 10:25 (15 mins) Yichao Yu, University College London |
10:20 | |||
10:25 | 10:25 | ||||
10:30 | 10:30 | ||||
10:35 | 10:35 | ||||
10:40 | Refreshment Break | 10:40 | |||
10:45 | 10:45 | ||||
10:50 | 10:50 | ||||
10:55 | 10:55 | ||||
11:00 | 11:00 | ||||
11:05 | 11:05 | ||||
11:10 | 11:10 | ||||
11:15 | Age-Old Challenges, Modern Solutions: The Role of Geroscience in Addressing Age-Related Diseases Chairs: Lynne Cox, University of Oxford Janet Lord, University of Birmingham Session Introduction 11:15 (5 mins) Lynne Cox, University of Oxford Janet Lord, University of Birmingham Longevity Pharmacology Comes of Age 11:20 (30 mins) Joao Pedro de Magalhaes, University of Birmingham Technology Spotlight Partner 11:50 (5 mins) Vendor Presentations, ELRIG From Target Engagement to Cellular Effect How to Position CETSA in the Drug Discovery Process 11:55 (15 mins) Yasmin Andersson — Pelago Bioscience AB UK SPINE, targeting drug discovery for age-related multimorbidity 12:10 (30 mins) Graeme Wilkinson, Medicines Discovery Catapult |
The rise of AI driven drug discovery Chairs: Kathryn Giblin, AstraZeneca Garry Pairaudeau, Exscientia Session Introduction 11:15 (5 mins) Kathryn Giblin, AstraZeneca Garry Pairaudeau, Exscientia Accelerating Drug Discovery with Computer Vision 11:20 (30 mins) Greg Slabaugh, Queen Mary University of London Technology Spotlight Partner 11:50 (5 mins) Vendor Presentations, ELRIG ML Tools in Drug Discovery 11:55 (15 mins) Thomas Waldmann, WuXi AppTec Predictive Minisci and P450 Late Stage Functionalization with Transfer Learning 12:10 (30 mins) Emma King-Smith, University of Cambridge |
11:15 | ||
11:20 | 11:20 | ||||
11:25 | 11:25 | ||||
11:30 | 11:30 | ||||
11:35 | 11:35 | ||||
11:40 | 11:40 | ||||
11:45 | 11:45 | ||||
11:50 | 11:50 | ||||
11:55 | 11:55 | ||||
12:00 | 12:00 | ||||
12:05 | 12:05 | ||||
12:10 | 12:10 | ||||
12:15 | 12:15 | ||||
12:20 | 12:20 | ||||
12:25 | 12:25 | ||||
12:30 | 12:30 | ||||
12:35 | 12:35 | ||||
12:40 | CoSolve sustainability live pitching event - Novel technologies to enable filter tip reuse or recycl Chairs: Kelly Gray, Emerging Innovations Unit, AstraZeneca CoSolve Finalist Presentation - Sustainable technologies to enable filter tip reuse and recycling in research and development 12:40 (10 mins) Katrina Cornish, The Ohio State University CoSolve Finalist Presentation - Using filters as new thermal insulation materials 12:50 (10 mins) Mohamed Ali, King Saud University CoSolve Finalist Presentation - Filter-remover box to recycle or reuse tips 13:00 (10 mins) Alberto Portone, TPM, Science & Technology Park for Medicine |
12:40 | |||
12:45 | 12:45 | ||||
12:50 | 12:50 | ||||
12:55 | 12:55 | ||||
1:00 | 1:00: | ||||
1:05: | 1:05: | ||||
1:10: | 1:10: | ||||
1:15: | 1:15: | ||||
1:20: | Refreshment Break - Poster Session 13.30 - 14.00 | 1:20: | |||
1:25: | 1:25: | ||||
1:30: | 1:30: | ||||
1:35: | 1:35: | ||||
1:40: | 1:40: | ||||
1:45: | 1:45: | ||||
1:50: | 1:50: | ||||
1:55: | 1:55: | ||||
2:00 | 2:00: | ||||
2:05: | 2:05: | ||||
2:10: | 2:10: | ||||
2:15: | 2:15: | ||||
2:20: | Age-Old Challenges, Modern Solutions: The Role of Geroscience in Addressing Age-Related Diseases Chairs: Lynne Cox, University of Oxford Janet Lord, University of Birmingham Oligonucleotide senotherapeutics for the diseases of ageing 14:20 (30 mins) Lorna Harries, Institute of Biomedical and Clinical Science, Medical School, College of Medicine and Health, Univer Providing in vivo data on ageing endpoints early in drug discovery 14:50 (30 mins) David Weinkove, Magnitude Biosciences Cryo-ET for investigating the role of respiratory chain organisation in health and disease 15:20 (10 mins) Emma Buzzard, University of Exeter |
The rise of AI driven drug discovery Chairs: Kathryn Giblin, AstraZeneca Garry Pairaudeau, Exscientia Learning rich molecular representations from quantum mechanics 14:20 (30 mins) Ward Haddadin, Exscientia Federated Learning in Drug Discovery 14:50 (30 mins) Lewis Mervin, AstraZeneca A novel in silico simulation platform to untangle biological pathway mechanisms in Type 1 Diabetes progression 15:20 (10 mins) Raminderpal Singh, Incubate.bio |
2:20: | ||
2:25: | 2:25: | ||||
2:30: | 2:30: | ||||
2:35: | 2:35: | ||||
2:40: | 2:40: | ||||
2:45: | 2:45: | ||||
2:50: | 2:50: | ||||
2:55: | 2:55: | ||||
3:00 | 3:00: | ||||
3:05: | 3:05: | ||||
3:10: | 3:10: | ||||
3:15: | 3:15: | ||||
3:20: | 3:20: | ||||
3:25: | 3:25: | ||||
3:30: | Comfort Break | 3:30: | |||
3:35: | 3:35: | ||||
3:40: | Age-Old Challenges, Modern Solutions: The Role of Geroscience in Addressing Age-Related Diseases Chairs: Lynne Cox, University of Oxford Janet Lord, University of Birmingham Strategies to target senescence 15:40 (30 mins) Jesus Gil, MRC London Institute of Medical Sciences Autophagy as a pathway to rejuvenate immune responses 16:10 (30 mins) Ghada Alsaleh, Oxford University |
The rise of AI driven drug discovery Chairs: Kathryn Giblin, AstraZeneca Garry Pairaudeau, Exscientia Mapping the Rare Disease Knowledge Graph 15:40 (30 mins) Daniel O'Donovan, healx Human-in-the-loop modelling for de novo molecular generation 16:10 (30 mins) Samuel Kaski, University of Manchester and Aalto University |
3:40: | ||
3:45: | 3:45: | ||||
3:50: | 3:50: | ||||
3:55: | 3:55: | ||||
4:00 | 4:00: | ||||
4:05: | 4:05: | ||||
4:10: | 4:10: | ||||
4:15: | 4:15: | ||||
4:20: | 4:20: | ||||
4:25: | 4:25: | ||||
4:30: | 4:30: | ||||
4:35: | 4:35: | ||||
4:40: | 4:40: | ||||
4:45: | 4:45: | ||||
4:50: | 4:50: | ||||
4:55: | 4:55: | ||||
5:00 | 5:00: | ||||
5:05: | 5:05: | ||||
5:10: | 5:10: | ||||
5:15: | 5:15: | ||||
5:20: | 5:20: | ||||
5:25: | 5:25: | ||||
5:30: | 5:30: | ||||
5:35: | 5:35: | ||||
5:40: | 5:40: | ||||
5:45: | 5:45: | ||||
5:50: | 5:50: | ||||
5:55: | 5:55: | ||||
6:00 | 6:00: | ||||
6:05: | 6:05: | ||||
6:10: | 6:10: | ||||
6:15: | 6:15: | ||||
6:20: | 6:20: | ||||
6:25: | 6:25: | ||||
6:30: | 6:30: | ||||
6:35: | 6:35: | ||||
6:40: | 6:40: | ||||
6:45: | 6:45: | ||||
6:50: | 6:50: | ||||
6:55: | 6:55: | ||||
7:00 | 7:00: |