Tue 4 October |
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DAY 1 | Auditorium 1 | Auditorium 2 | Auditorium 3 | Auditorium 4 |
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8:00 | Registration | Early Career Professional (ECP) Meet & Greet |
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9:10: | ELRIG Annual Review Chairs: Catherine Kettleborough, LifeArc, The Accelerator Sanj Kumar, ELRIG |
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9:30: | Conference Welcome and Keynote Introduction Chairs: Katie Chapman, VC funded Biotech Company Simon Chell, AstraZeneca Jon Hutchinson, GlaxoSmithKline Simon Ward, University of Cardiff |
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9:35: | Keynote Presentation New technologies for the design and characterisation of nanotechnology mediated therapeutics 09:35 (45 mins) Molly Stevens, Imperial College London |
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10:20 | Refreshment Break | DDW - Taking your first steps towards liquid handling automation - Sponsored by SPT Labtech Chairs: Anne Hammerstein, SPT Labtech |
Langton Howarth- Understanding the needs of talent acquisition departments to start a career in a life-science corporations: Ask an Expert!’ Chairs: Chris Luche, Sanger Institute Sue Ward, Illumina |
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11:05 | High Content Imaging in Drug Discovery Chairs: Sian Lewis, MSD Michael Howell, The Francis Crick Institute Session Introduction 11:05 (5 mins) Sian Lewis, MSD Michael Howell, The Francis Crick Institute High Content Imaging as an enabling tool for early drug discovery 11:10 (30 mins) John Bassett, MSD Patient-Derived Cell (PDC) Models as a Tool to Assess Cancer Therapeutic Efficacy Across the Drug Development Life Cycle 11:40 (30 mins) Rachel Howard-Jones — Nexcelom from PerkinElmer Accelerating Drug Discovery with Cell Painting 12:10 (30 mins) James Pilling, AstraZeneca Microplate readers and imaging systems 12:40 (5 mins) Imran Haneef — LabLogic Systems Limited |
Overcoming Challenges and New Directions in Medicinal Chemistry Chairs: Allan Jordan, Sygnature Discovery Sarah Skerrat, CHARM Therapeutics Session Introduction 11:05 (5 mins) Allan Jordan, Sygnature Discovery Sarah Skerrat, CHARM Therapeutics Discovery and validation of in vitro and in vivo probes for human DNA Polymerase theta (Polθ) 11:10 (30 mins) Robert Heald, Artios Pharma The COVID Moonshot – from open science collaboration in fragment screening to drug candidate and beyond to Pandemic Preparedness 11:40 (30 mins) Ed Griffen, MedChemica Ltd ML/AI: Opportunities, Impact and Future Directions in Drug Design 12:10 (30 mins) Sarah Skerrat, CHARM Therapeutics |
Cell & Gene Therapy Sponsored by Miltenyi Chairs: Chris Herring, Adaptimmune Claire Dobson, AstraZeneca Session Introduction 11:05 (5 mins) Chris Herring, Adaptimmune Claire Dobson, AstraZeneca TCR Evolution, revolution: How Adaptimmune is developing innovative TCR T-cell therapies to treat solid tumors 11:10 (30 mins) Jo Brewer, Adaptimmune Limited The journey from discovery to therapy begins with a single cell 11:40 (30 mins) Stephen Hague — 10x Genomics From Stem-Cells to T-Cells: Next-Generation DNA NanoVectors -an Alternative Non-Integrating DNA Vector Platform for Regenerative Medicine and Immunotherapy 12:10 (30 mins) Richard Harbottle, German Cancer Research Centre (DKFZ) Automating high-throughput NGS and qPCR assays: Meet the Biomark™ X and the Juno™ 12:40 (5 mins) James Curtis — Standard Bio Tools |
Drug Discovery and Development in COPD Chairs: Anna Morgan, Physiology & Pharmacology, Kingston University Simon Pitchford, King's College London Session Introduction 11:05 (5 mins) Anna Morgan, Physiology & Pharmacology, Kingston University Simon Pitchford, King's College London The burden of unmet needs in COPD 11:10 (30 mins) Wisia Wedzicha, Imperial College London Novel drug targets in COPD 11:40 (30 mins) Ian Adcock, Imperial College London New perspectives for modelling inflammatory diseases using patient-derived organoids 12:10 (5 mins) Sylvia F. Boj — HUB Organoids Use of Imaging for preclinical evaluation of drugs for the treatment of COPD 12:15 (30 mins) Anna Morgan, Physiology & Pharmacology, Kingston University |
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12:45 | Refreshment Break - Poster Session 13.15 - 13.45 | DDW - The role of AI and automation in personalised medicine: How can AI help in the post drug discovery process. Chairs: Yahya Anvar, OKRA.ai |
Cytek Bio Workshop - Full Spectrum Profiling (FSP)™, adaptable solutions to deep immunophenotyping using the Cytek Aurora: a practical walkthrough |
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1:20: | DDW - Data handling and choosing the right informatics systems for your lab requirements - Sponsored by CDD Chairs: Samantha Kanza, University of Southampton |
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2:00 | High Content Imaging in Drug Discovery Phenonaut; a tool for multiomic data integration, analysis, prediction, and inference 14:00 (30 mins) Steven Shave, University of Edinburgh & GSK 10x Your Lab: High Content Analysis Meets High-Throughput Screening 14:30 (5 mins) Kristin Halfpenny — Araceli Biosciences spheroONE – an automated high throughput spheroid isolation and manipulation technology. 14:35 (5 mins) Alice Cheesbrough — Cellenion Life beyond the pixels: single-cell analysis using deep learning and image analysis methods 14:40 (30 mins) Peter Horvath, Biological Research Centre, Szeged |
Overcoming Challenges and New Directions in Medicinal Chemistry Optimising proteolysis-targeting chimeras (PROTACs) for oral drug delivery - Design tips and tricks 14:00 (30 mins) Jamie Scott, AstraZeneca Supporting innovations in Splicesome research 14:30 (5 mins) ROSLYN McConnell — Avantor New Approaches to the Synthesis and Application of DNA-Encoded Libraries 14:35 (30 mins) Jessica Graham, Newcastle University Harriet Stanway-Gordon, Newcastle University |
Cell & Gene Therapy Sponsored by Miltenyi Pin-point™ – A Modular Base Editing System Driving Cell and Gene therapies 14:00 (30 mins) Michael Anbar, Horizon Discovery, a PerkinElmer company Assist Plus Pipetting Platform 14:30 (5 mins) Sharon Barnard — INTEGRA Biosciences Bioluminescent assay tools for TCR-T and CAR-T development and characterisation 14:35 (5 mins) Craig Malcolm — Promega UK Ltd Armouring CAR-T cells therapy against the immunosuppressive microenvironment in solid tumour 14:40 (30 mins) Romain Lara, AstraZeneca |
Drug Discovery and Development in COPD Preclinical translational models for investigating drugs for the treatment of COPD 14:00 (30 mins) Simon Pitchford, King's College London Use of human tissues to investigate drugs for the treatment of COPD 14:30 (30 mins) Luigino Calzetta, University of Parma |
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3:10: | Refreshment Break | 3:10: | |||||
3:15: | DDW - Accelerating Drug Discovery: Getting to the right molecule smarter & faster with automation- Sponsored by Bio Rad Chairs: Zoe Hughes-Thomas, GSK |
Singular Talent - Growing your company through great story telling Chairs: Tom Froggatt, Singular Talent |
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3:45: | High Content Imaging in Drug Discovery Morphological trajectory inference: Tracking cell state transitions and the impact of small-molecule perturbations 15:45 (30 mins) Rebecca Hughes, University of Edinburgh Magnetic Electrospun Microfibre Scaffold Assemblies: Examples of there use for Cell-Based Screening Applications 16:15 (15 mins) Gary Allenby — Charnwood Molecular Quantitative high-throughput screening of single cancer cell phenotypes in 3D matrices 16:30 (30 mins) Vicky Bousgouni, Institute of Cancer Research |
Overcoming Challenges and New Directions in Medicinal Chemistry Targeting the template: A novel therapeutic strategy for prion diseases 15:45 (30 mins) Heulyn Jones, Cardiff University Navigate Your Chemistry And Explore The Biology - Case Studies Of CETSA® overcoming challenges in Drug Discovery 16:15 (15 mins) Isabel Martin Caballero — Pelago Bioscience AB Audience Lead Panel Discussion with Q&A 16:30 (30 mins) Allan Jordan, Sygnature Discovery Sarah Skerrat, CHARM Therapeutics |
Cell & Gene Therapy Sponsored by Miltenyi Unlocking a revolutionary class of in vivo reprogramming therapies through systematic, unbiased identification of the key cell switches controlling cell fate 15:45 (30 mins) Louise Modis, Mogrify The impact of not understanding the genetic landscape, Ignorance will cost you time and money. 16:15 (15 mins) Melanie Maerken — Synthego Next Generation Platforms for Human Gene Therapy 16:30 (30 mins) Aravind Asokan, Duke University |
Drug Discovery and Development in COPD Early experimental medicine studies for investigating new drugs for COPD 15:45 (30 mins) Dave Singh, University of Manchester Methods to tackle novel molecular targets involved in inflammatory disease 16:15 (15 mins) Mark Abbott — Peak Proteins Ltd Publishing in the British Journal of Pharmacology 16:30 (30 mins) Charles Whalley, British Pharmacological Society |
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5:00 | Networking Event - Poster Session 18.30 - 19.00 |
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5:15: | Early Career Professionals: Careers in drug discovery - Network like a Boss |
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7:00 | ELRIG’s Celebration of Drug Discovery, sponsored by Synthego, at The Fox, ExCel |
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