Drug Discovery 2022: driving the next life science revolution

Tue 4 October
5 October
[Schedule with Sessions only]
DAY 1Auditorium 1Auditorium 2Auditorium 3Auditorium 4
DAY 2
8:00 Registration
Early Career Professional (ECP) Meet & Greet
 8:00:
8:05: 8:05:
8:10: 8:10:
8:15: 8:15:
8:20: 8:20:
8:25: 8:25:
8:30: 8:30:
8:35: 8:35:
8:40: 8:40:
8:45: 8:45:
8:50: 8:50:
8:55: 8:55:
9:00 9:00:
9:05: 9:05:
9:10:
ELRIG Annual Review
Chairs: Catherine Kettleborough, LifeArc, The Accelerator  Sanj Kumar, ELRIG  
 9:10:
9:15: 9:15:
9:20: 9:20:
9:25: 9:25:
9:30:
Conference Welcome and Keynote Introduction
Chairs: Katie Chapman, VC funded Biotech Company   Simon Chell, AstraZeneca  Jon Hutchinson, GlaxoSmithKline  Simon Ward, University of Cardiff  
 9:30:
9:35:
Keynote Presentation
New technologies for the design and characterisation of nanotechnology mediated therapeutics
09:35 (45 mins)
Molly Stevens, Imperial College London  
 9:35:
9:40: 9:40:
9:45: 9:45:
9:50: 9:50:
9:55: 9:55:
10:00 10:00
10:05 10:05
10:10 10:10
10:15 10:15
10:20 Refreshment Break
DDW - Taking your first steps towards liquid handling automation - Sponsored by SPT Labtech
Chairs: Anne Hammerstein, SPT Labtech  
Langton Howarth- Understanding the needs of talent acquisition departments to start a career in a life-science corporations: Ask an Expert!’
Chairs: Chris Luche, Sanger Institute  Sue Ward, Illumina  
 10:20
10:25 10:25
10:30 10:30
10:35 10:35
10:40 10:40
10:45 10:45
10:50 10:50
10:55 10:55
11:00 11:00
11:05
High Content Imaging in Drug Discovery
Chairs: Sian Lewis, MSD  Michael Howell, The Francis Crick Institute  
Session Introduction
11:05 (5 mins)
Sian Lewis, MSD  Michael Howell, The Francis Crick Institute  
High Content Imaging as an enabling tool for early drug discovery
11:10 (30 mins)
John Bassett, MSD  
Patient-Derived Cell (PDC) Models as a Tool to Assess Cancer Therapeutic Efficacy Across the Drug Development Life Cycle
11:40 (30 mins)
Rachel Howard-Jones — Nexcelom from PerkinElmer     
Accelerating Drug Discovery with Cell Painting
12:10 (30 mins)
James Pilling, AstraZeneca  
Microplate readers and imaging systems
12:40 (5 mins)
Imran Haneef — LabLogic Systems Limited    
Overcoming Challenges and New Directions in Medicinal Chemistry
Chairs: Allan Jordan, Sygnature Discovery  Sarah Skerrat, CHARM Therapeutics  
Session Introduction
11:05 (5 mins)
Allan Jordan, Sygnature Discovery  Sarah Skerrat, CHARM Therapeutics  
Discovery and validation of in vitro and in vivo probes for human DNA Polymerase theta (Polθ)
11:10 (30 mins)
Robert Heald, Artios Pharma  
The COVID Moonshot – from open science collaboration in fragment screening to drug candidate and beyond to Pandemic Preparedness
11:40 (30 mins)
Ed Griffen, MedChemica Ltd  
ML/AI:  Opportunities, Impact and Future Directions in Drug Design
12:10 (30 mins)
Sarah Skerrat, CHARM Therapeutics  
Cell & Gene Therapy Sponsored by Miltenyi
Chairs: Chris Herring, Adaptimmune  Claire Dobson, AstraZeneca  
Session Introduction
11:05 (5 mins)
Chris Herring, Adaptimmune  Claire Dobson, AstraZeneca  
TCR Evolution, revolution: How Adaptimmune is developing innovative TCR T-cell therapies to treat solid tumors
11:10 (30 mins)
Jo Brewer, Adaptimmune Limited  
The journey from discovery to therapy begins with a single cell
11:40 (30 mins)
Stephen Hague — 10x Genomics    
From Stem-Cells to T-Cells: Next-Generation DNA NanoVectors -an Alternative Non-Integrating DNA Vector Platform for Regenerative Medicine and Immunotherapy
12:10 (30 mins)
Richard Harbottle, German Cancer Research Centre (DKFZ)  
Automating high-throughput NGS and qPCR assays: Meet the Biomark™ X and the Juno™
12:40 (5 mins)
James Curtis — Standard Bio Tools    
Drug Discovery and Development in COPD
Chairs: Anna Morgan, Physiology & Pharmacology, Kingston University  Simon Pitchford, King's College London  
Session Introduction
11:05 (5 mins)
Anna Morgan, Physiology & Pharmacology, Kingston University  Simon Pitchford, King's College London  
The burden of unmet needs in COPD
11:10 (30 mins)
Wisia Wedzicha, Imperial College London  
Novel drug targets in COPD
11:40 (30 mins)
Ian Adcock, Imperial College London  
New perspectives for modelling inflammatory diseases using patient-derived organoids
12:10 (5 mins)
Sylvia F. Boj — HUB Organoids    
Use of Imaging for preclinical evaluation of drugs for the treatment of COPD
12:15 (30 mins)
Anna Morgan, Physiology & Pharmacology, Kingston University  
 11:05
11:10 11:10
11:15 11:15
11:20 11:20
11:25 11:25
11:30 11:30
11:35 11:35
11:40 11:40
11:45 11:45
11:50 11:50
11:55 11:55
12:00 12:00
12:05 12:05
12:10 12:10
12:15 12:15
12:20 12:20
12:25 12:25
12:30 12:30
12:35 12:35
12:40 12:40
12:45 Refreshment Break - Poster Session 13.15 - 13.45
DDW - The role of AI and automation in personalised medicine: How can AI help in the post drug discovery process.
Chairs: Yahya Anvar, OKRA.ai  
Cytek Bio Workshop - Full Spectrum Profiling (FSP)™, adaptable solutions to deep immunophenotyping using the Cytek Aurora: a practical walkthrough
 12:45
12:50 12:50
12:55 12:55
1:00 1:00:
1:05: 1:05:
1:10: 1:10:
1:15: 1:15:
1:20:
DDW - Data handling and choosing the right informatics systems for your lab requirements - Sponsored by CDD
Chairs: Samantha Kanza, University of Southampton  
 1:20:
1:25: 1:25:
1:30: 1:30:
1:35: 1:35:
1:40: 1:40:
1:45: 1:45:
1:50: 1:50:
1:55: 1:55:
2:00
High Content Imaging in Drug Discovery
Phenonaut; a tool for multiomic data integration, analysis, prediction, and inference
14:00 (30 mins)
Steven Shave, University of Edinburgh & GSK  
10x Your Lab: High Content Analysis Meets High-Throughput Screening
14:30 (5 mins)
Kristin Halfpenny — Araceli Biosciences    
spheroONE – an automated high throughput spheroid isolation and manipulation technology.
14:35 (5 mins)
Alice Cheesbrough — Cellenion    
Life beyond the pixels: single-cell analysis using deep learning and image analysis methods
14:40 (30 mins)
Peter Horvath, Biological Research Centre, Szeged  
Overcoming Challenges and New Directions in Medicinal Chemistry
Optimising proteolysis-targeting chimeras (PROTACs) for oral drug delivery - Design tips and tricks
14:00 (30 mins)
Jamie Scott, AstraZeneca  
Supporting innovations in Splicesome research
14:30 (5 mins)
ROSLYN McConnell — Avantor    
New Approaches to the Synthesis and Application of DNA-Encoded Libraries
14:35 (30 mins)
Jessica Graham, Newcastle University  Harriet Stanway-Gordon, Newcastle University  
Cell & Gene Therapy Sponsored by Miltenyi
Pin-point™ – A Modular Base Editing System Driving Cell and Gene therapies
14:00 (30 mins)
Michael Anbar, Horizon Discovery, a PerkinElmer company  
Assist Plus Pipetting Platform
14:30 (5 mins)
Sharon Barnard — INTEGRA Biosciences    
Bioluminescent assay tools for TCR-T and CAR-T development and characterisation
14:35 (5 mins)
Craig Malcolm — Promega UK Ltd    
Armouring CAR-T cells therapy against the immunosuppressive microenvironment in solid tumour
14:40 (30 mins)
Romain Lara, AstraZeneca  
Drug Discovery and Development in COPD
Preclinical translational models for investigating drugs for the treatment of COPD
14:00 (30 mins)
Simon Pitchford, King's College London  
Use of human tissues to investigate drugs for the treatment of COPD
14:30 (30 mins)
Luigino Calzetta, University of Parma   
 2:00:
2:05: 2:05:
2:10: 2:10:
2:15: 2:15:
2:20: 2:20:
2:25: 2:25:
2:30: 2:30:
2:35: 2:35:
2:40: 2:40:
2:45: 2:45:
2:50: 2:50:
2:55: 2:55:
3:00 3:00:
3:05: 3:05:
3:10: Refreshment Break 3:10:
3:15:
DDW - Accelerating Drug Discovery: Getting to the right molecule smarter & faster with automation- Sponsored by Bio Rad
Chairs: Zoe Hughes-Thomas, GSK  
Singular Talent - Growing your company through great story telling
Chairs: Tom Froggatt, Singular Talent  
 3:15:
3:20: 3:20:
3:25: 3:25:
3:30: 3:30:
3:35: 3:35:
3:40: 3:40:
3:45:
High Content Imaging in Drug Discovery
Morphological trajectory inference: Tracking cell state transitions and the impact of small-molecule perturbations
15:45 (30 mins)
Rebecca Hughes, University of Edinburgh  
Magnetic Electrospun Microfibre Scaffold Assemblies: Examples of there use for Cell-Based Screening Applications
16:15 (15 mins)
Gary Allenby — Charnwood Molecular     
Quantitative high-throughput screening of single cancer cell phenotypes in 3D matrices
16:30 (30 mins)
Vicky Bousgouni, Institute of Cancer Research  
Overcoming Challenges and New Directions in Medicinal Chemistry
Targeting the template: A novel therapeutic strategy for prion diseases
15:45 (30 mins)
Heulyn Jones, Cardiff University  
Navigate Your Chemistry And Explore The Biology - Case Studies Of CETSA® overcoming challenges in Drug Discovery
16:15 (15 mins)
Isabel Martin Caballero — Pelago Bioscience AB    
Audience Lead Panel Discussion with Q&A
16:30 (30 mins)
Allan Jordan, Sygnature Discovery  Sarah Skerrat, CHARM Therapeutics  
Cell & Gene Therapy Sponsored by Miltenyi
Unlocking a revolutionary class of in vivo reprogramming therapies through systematic, unbiased identification of the key cell switches controlling cell fate
15:45 (30 mins)
Louise Modis, Mogrify  
The impact of not understanding the genetic landscape, Ignorance will cost you time and money.
16:15 (15 mins)
Melanie Maerken — Synthego     
Next Generation Platforms for Human Gene Therapy
16:30 (30 mins)
Aravind Asokan, Duke University   
Drug Discovery and Development in COPD
Early experimental medicine studies for investigating new drugs for COPD
15:45 (30 mins)
Dave Singh, University of Manchester  
Methods to tackle novel molecular targets involved in inflammatory disease
16:15 (15 mins)
Mark Abbott — Peak Proteins Ltd    
Publishing in the British Journal of Pharmacology
16:30 (30 mins)
Charles Whalley, British Pharmacological Society  
 3:45:
3:50: 3:50:
3:55: 3:55:
4:00 4:00:
4:05: 4:05:
4:10: 4:10:
4:15: 4:15:
4:20: 4:20:
4:25: 4:25:
4:30: 4:30:
4:35: 4:35:
4:40: 4:40:
4:45: 4:45:
4:50: 4:50:
4:55: 4:55:
5:00
Networking Event - Poster Session 18.30 - 19.00
 5:00:
5:05: 5:05:
5:10: 5:10:
5:15:
Early Career Professionals: Careers in drug discovery - Network like a Boss
 5:15:
5:20: 5:20:
5:25: 5:25:
5:30: 5:30:
5:35: 5:35:
5:40: 5:40:
5:45: 5:45:
5:50: 5:50:
5:55: 5:55:
6:00 6:00:
6:05: 6:05:
6:10: 6:10:
6:15: 6:15:
6:20: 6:20:
6:25: 6:25:
6:30: 6:30:
6:35: 6:35:
6:40: 6:40:
6:45: 6:45:
6:50: 6:50:
6:55: 6:55:
7:00
ELRIG’s Celebration of Drug Discovery, sponsored by Synthego, at The Fox, ExCel
 7:00: