Drug Discovery 2021 After the Storm: Re-connect, Re-invent, Re-imagine

Tue 19 October

20 October

[Schedule with Sessions only]

DAY 1	Room 3A	Room 3B	Hall 1B	Hall 1C	Room 11B - Workshop	Careers Zone, Main Exhibition Hall	DAY 2
8:00	Event Registration					Early Career Professional Welcome Early Career Professional Welcome 08:00 (45 mins) Lisa Stott, Sosei Heptares	8:00:
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8:45:	ELRIG - Opening Session ELRIG - Annual Review - Visons & Values 08:45 (10 mins) Melanie Leveridge, GSK   ELRIG - Equality, Diversity & Inclusion Guiding Principals 08:55 (5 mins) Clare Viney, Vitae   ELRIG - Lifetime Achievement Award - A Career In Drug Discovery 09:00 (20 mins) Steve Rees, AstraZeneca   Innovation and Automation during a Pandemic 09:20 (50 mins) Rob Howes, DHSC						8:45:
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10:10	Refreshment Break						10:10
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10:50	New Approaches in Infection Biology Chairs: David Pallin, CRL  Adrian Goldman, U. Helsinki	Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd Chairs: Nikki Carter, Excalibur Healthcare  Emily Adams, Liverpool School of Tropical Medicine and Mologic	Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA Chairs: Wesley Blackaby, Servier  Oliver Rausch, Storm Therapeutics Ltd	Alzheimer’s Research UK Chairs: John Isaac, Janssen Neuroscience  David Reynolds, AstronauTx Ltd	Workshop Gaining a career in industry: Learning tips and tricks from the inside 10:50 (60 mins) Allan Jordan, Sygnature Discovery		10:50
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11:00	New Approaches in Infection Biology Neuropilin-1 facilitates SARS-CoV2 cell entry and infectivity 11:00 (30 mins) Maria Anastasina, University of Helsinki   Diverse neutralizing SARS-CoV-2 antibodies identified from large-scale synthetic phage libraries target rare epitopes and retain binding to variants of concern. 11:30 (30 mins) Tom Yuan — Twist Bioscience	Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd Q-POCTM, a paradigm shift in rapid multiplex molecular diagnostics 11:00 (30 mins) Jonathan OHalloran, QuantumDx   Transforming Drug Discovery Through Precision Research 11:30 (30 mins) Stephen Hague — 10x Genomics	Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA Discovery of risdiplam (evrysdi) - A medicine for the treatment of spinal muscular atrophy 11:00 (30 mins) Hasane Ratni , F. Hoffmam-La Roche   A Fully Automated Data Analysis Workflow for Gene Expression-Based Screening 11:30 (30 mins) Gabriela Nass Kovacs — Genedata AG	Alzheimer’s Research UK Alzheimer’s Research UK and its support for translational research. 11:00 (30 mins) Sara Imarisio, ARUK   Coding cells for health: building translational disease models for drug discovery and therapeutics 11:30 (30 mins) Sara Gomes — bit.bio    Marta Rucka — bit.bio			11:00
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12:00	New Approaches in Infection Biology Functional analysis of Bartonella pathogenicity factors might contribute to novel therapeutic concepts 12:00 (30 mins) Volkhard Kempf , Goethe University of Frankfurt am Main	Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd A luminescent reporter cell line for authentic SARS-CoV-2 infection and neutralising antibody activity 12:00 (30 mins) Nick Matheson, University of Cambridge	Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA mRNA Lightning platform for the discovery of selective small molecule mRNA regulatory drugs 12:00 (30 mins) Iris Alroy, Anima Biotech	Alzheimer’s Research UK Identification of tool compounds targeting the SRSF1-dependent nuclear export of pathological C9ORF72-repeat transcripts 12:00 (30 mins) Lianne Van Beek, CRL  Tennore Ramesh, Sheffield Institute for Translational Neuroscience (SITraN)			12:00
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12:30	Refreshment Break				Workshop Chairs: Lilian Hunt, EDIS, Wellcome Trust   Inclusive research and experimental design 12:30 (60 mins) Lilian Hunt, EDIS, Wellcome Trust		12:30
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2:00	New Approaches in Infection Biology Targeting the human RED-SMU1 splicing complex as a basis for host-directed anti-influenza therapy 14:00 (30 mins) Nadia Naffakh, Institut Pasteur, CNRS   Introducing TRFID, a UK-leading BSL3 translation biology facility for Infectious Diseases at Alderley Park 14:30 (5 mins) Helen Bright — Medicines Discovery Catapult     LabLogic Life Sciences range has something for everyone 14:35 (5 mins) Lucy Farmer — LabLogic Systems Limited     FidaBio: Characterizing Biomolecular behaviour by measuring and monitoring changes in hydrodynamic radius 14:40 (5 mins) Jo Walter — Fida Biosystems ApS	Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd Diagnostics for epidemics, pandemics and neglected tropical disease 14:00 (30 mins) Emily Adams, Liverpool School of Tropical Medicine and Mologic    Mesoporous silica & PLGA nanoparticles for next-generation drug delivery & targeted therapeutic technologies 14:30 (5 mins) Philippe Saint-Cricq-Riviere — nanoComposix     Assist Plus 14:35 (5 mins) Sharon Barnard — INTEGRA Biosciences	Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA Dynamic RNAs and Structure-Guided Small Molecule Drug Discovery 14:00 (30 mins) Isaac Kimsey, Nymirum  Yang Zheng, Nymirum   DNA-Encoded Library Technology for Drug Discovery 14:30 (5 mins) Assunta Romano — Merck Life Science	Alzheimer’s Research UK Small molecule inhibitors of carboxylesterase Notum to potentiate Wnt signalling 14:00 (30 mins) Nicky Willis, UCL DDI   Quantifying Morphological Change Using Label-Free Live-Cell Analysis 14:30 (15 mins) Jasmine Trigg — Sartorius	Workshop Chairs: Anita Ramanathan, Word Cortex   Exceptional Science Presentations: How to Effectively Communicate the Value of Your Work 14:00 (45 mins) Anita Ramanathan, Word Cortex		2:00:
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2:35:			Tecan UK Ltd				2:35:
2:40:			Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA Integrated Drug Discovery: Chemistry and Biology working together to create innovative solutions 14:40 (5 mins) Catherine Stace — Domainex				2:40:
2:45:	New Approaches in Infection Biology Studies of the membrane-bound pyrophosphatase as a potential drug target against protist parasites 14:45 (30 mins) Keni Vidilaseris, University of Helsinki	Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd EMERGING DIAGNOSTIC TECHNOLOGIES IN CLINICAL MICROBIOLOGY 14:45 (30 mins) Alex Van Belkum, Biomeirieux	Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA Small activating RNAs from concept to Phase 2 clinical trial 14:45 (30 mins) Vikash Reebye  Nagy Habib , MiNA Therapeutics	Alzheimer’s Research UK Development of eIF2B modulators for the treatment of neurodegenerative disease 14:45 (30 mins) Duncan Scott, Alborada Drug Discovery Institute, Cambridge			2:45:
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3:15:	Refreshment Break						3:15:
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3:45:	New Approaches in Infection Biology Developing inhibitors that block adhesin-collagen interactions 15:45 (30 mins) Dirk Linke, University of Oslo   PerkinElmer’s Tools to study virus-host interaction and virus inhibition 16:15 (15 mins) Louise Affleck — PerkinElmer	Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd Computer literate? Novel AI based reading of lateral flow devices 15:45 (30 mins) Daniel Wise, Excalibur Healthcare   Design your molecular-based assays with confidence: Using ATCC’s Genome Portal bioinformatics platform to select wide-ranging, sequence-verified materials 16:15 (5 mins) Rebecca Charlton — LGC - ATCC     Don't Let the Antibody be a Variable in Your Assay 16:20 (5 mins) Mark Twigden — Cell Signaling Technology     Introducing Cytek cFluorTM Reagents and Assays 16:25 (5 mins) Michelle Jackson — Cytek Bio	Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA Drugging RNA Modifying Enzymes – METTL3 Inhibitors as a novel therapeutic strategy for Acute Myeloid Leukemia 15:45 (30 mins) David Hardick, Storm Therapeutics  Konstantinos Tzelepis , The Milner Therapeutics Institute	Alzheimer’s Research UK Gene editing to treat expanded CAG/CTG repeat disorders 15:45 (30 mins) Vincent Dion, Cardiff Dementia Research Institute   The new generation of live cell shipments 16:15 (5 mins) Simon Myrbäck — Cellbox Solutions     High-Throughput Genome Editing for Disease Models 16:20 (5 mins) Nick Clare — Synthego      Ulysses - Arctoris' end-to-end automation platform for accelerated drug discovery 16:25 (5 mins) Daniel Thomas — Arctoris Ltd	Workshop How to select the best nanoparticle for next-gen drug delivery 15:45 (60 mins) Philippe Saint-Cricq-Riviere — nanoComposix		3:45:
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4:15:			Technology Spotlights				4:15:
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4:30:	New Approaches in Infection Biology Inhibition of bacterial virulence as an alternative to antibiotic treatment: Pseudomonas aeruginosa elastase as a target for antivirulence therapy 16:30 (30 mins) Martin Everett, Antabio	Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd How to build a mobile lab for genomic surveillance of viral outbreaks 16:30 (30 mins) Joshua Quick, Institute of Microbiology and infection, University of Birmingham	Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA X-reactivation as an approach to treating Rett Syndrome 16:30 (30 mins) Jeannie Lee, Harvard	Alzheimer’s Research UK Novel Therapeutic Targets for Treatment of Neurodegeneration 16:30 (30 mins) Paul Brennan, Oxford DDI			4:30:
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5:00	Networking & Posters						5:00:
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