Abstract

Unlock the power of CRISPR at the SciLIfeLab CRISPR Functional Genomics unit (CFG)! We provide affordable access to precision-editing and massively parallel functional genomic screens using various CRISPR-systems. Massively parallel perturbation in pooled CRISPR screens lets you investigate tens of thousands of genes or genetic elements for their involvement in the biological processes that matter to you. CFG offers access to verified lentiviral CRISPR guide libraries for whole-genome or targeted loss- and gain-of-function studies, including CRISPR-KO, CRISPR-i, and CRISPR-a. To meet your unique research needs, we create any custom guide library - from design to packaged lentivirus. We are constantly innovating and are developing base-editing approaches for mutagenesis screens to study protein-drug interactions, as well as optical pooled screens allowing complex phenotypic readouts.